Evidence map›Paper›PMID 33975835›Full record

ArticleBMJ case reports2021

Creutzfeldt-Jakob disease as a cause of dementia.

Rasha Nakhleh, Sophia Tenaye Tessema, Abdullahi Mahgoub

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Rasha NakhlehInternal Medicine and Geriatrics, Oregon Health and Science University, Portland, Oregon, USA nakhlehr@ohsu.edu.ORCID http://orcid.org/0000-0002-7719-0135
Sophia Tenaye TessemaCollege of Human Medicine, Michigan State University, East Lansing, Michigan, USA.ORCID http://orcid.org/0000-0003-2632-8277
Abdullahi MahgoubInternal Medicine, Hurley Medical Center, Flint, Michigan, USA.ORCID http://orcid.org/0000-0002-5628-7202
Hurley Medical Center · USMichigan State University · USOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, fatal neurodegenerative disorder belonging to the family of transmissible spongiform encephalopathies. The disease is believed to be caused by an abnormal isoform of a cellular glycoprotein known as the prion protein. Our patient is an 84-year-old Caucasian man who presented to the geriatric clinic for evaluation of short-term memory loss and decreased concentration which started 3 months prior to initial evaluation. Rapid progression of dementia demonstrated by severe impairment in tasks with a predominantly visual component, including visual scanning, perceptual reasoning and visual spatial processing. Diagnosis of CJD was determined by characteristic ribboning on brain MRI as well as notable real-time quaking-induced conversion on cerebrospinal fluid.

Indexed as

Creutzfeldt-Jakob SyndromePrion DiseasesAgedAged, 80 and overHumansMagnetic Resonance ImagingMalegeneral practice / family medicinememory disordersneuroimaging

Identifiers

PMID33975835
PMCPMC8118005
OpenAlexW3162401945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.