Evidence map›Paper›PMID 33975779›Full record

ReviewTrends in parasitology2021

SchistoCyte Atlas: A Single-Cell Transcriptome Resource for Adult Schistosomes.

George R Wendt, Michael L Reese, James J Collins

Open access · greenAbstract readReview
In one paragraph

Review in Trends in parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. An injury-responsivebioRxiv : the preprint server for biology · 2026
    Article
  4. Plant-Derived Terpenes as Emerging Therapeutics Against Schistosomiasis.International journal of molecular sciences · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Schistosomiasis.Advances in experimental medicine and biology · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George R WendtDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, TX, USA.
Michael L ReeseDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, TX, USA; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX, USA.
James J CollinsDepartment of Pharmacology, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: JamesJ.Collins@UTSouthwestern.edu.
Southwestern Medical Center · US

Funding

The Biology of Stem Cells in the Human Parasite Schistosoma MansoniR01AI121037 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI COLLINS, JAMES J · 2016 to 2025
$4.4M
Characterizing sexual development of the human parasite Schistosoma mansoniR01AI150776 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI COLLINS, JAMES J · 2020 to 2024
$2.7M
Kinase regulation of trafficking at the Toxoplasma intravacuolar networkR01AI150715 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI REESE, MICHAEL LLOYD · 2020 to 2024
$2.0M
NIAID NIH HHS R01 AI121037NIAID NIH HHS R01 AI150715NIAID NIH HHS R01 AI150776
6 · The paper itself

Abstract

Schistosomes cause untold disease and disability in the developing world. Here, we introduce SchistoCyte Atlas, a web-based platform for exploring gene expression at single-cell resolution in adult Schistosoma mansoni. Similar resources accessible to non-specialists across the globe will expedite our ability to understand the biology of these devastating parasites.

Indexed as

TranscriptomeAnimalsHelminth ProteinsLife Cycle StagesSchistosoma mansoniHelminth ProteinsRNAi screeningschistosomesingle-cell RNAseqweb-based resource

Identifiers

PMID33975779
PMCPMC8721880
OpenAlexW3160045890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.