Evidence map›Paper›PMID 33975766›Full record

ArticleAmerican journal of preventive medicine2021

Dental Opioid Prescriptions and Overdose Risk in Patients and Their Families.

Kao-Ping Chua, Brooke C Kenney, Jennifer F Waljee, Chad M Brummett, Romesh P Nalliah

Open access · greenAbstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kao-Ping ChuaSusan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan; Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, Michigan. Electronic address: chuak@med.umich.edu.
Brooke C KenneyMichigan Opioid Prescribing Engagement Network, Ann Arbor, Michigan.
Jennifer F WaljeeMichigan Opioid Prescribing Engagement Network, Ann Arbor, Michigan; Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan.
Chad M BrummettMichigan Opioid Prescribing Engagement Network, Ann Arbor, Michigan; Division of Pain Medicine, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.
Romesh P NalliahUniversity of Michigan School of Dentistry, Ann Arbor, Michigan.
University of Michigan–Ann Arbor · USMichigan United · US

Funding

Using Default Opioid Prescription Settings to Limit Excessive Opioid Prescribing to Adolescents and Young AdultsK08DA048110 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHUA, KAO-PING · 2019 to 2023
$983k
NIDA NIH HHS K08 DA048110
6 · The paper itself

Abstract

introductionIt is unknown whether dental opioid prescriptions are associated with opioid overdose in patients or their family members, who may have access to patients' opioids.

methodsDuring July-October 2020, the 2011-2018 IBM MarketScan Dental, IBM MarketScan Commercial, and Medicaid Multi-State Databases were analyzed. Two analyses were conducted. In the patient analysis, dental procedures for privately and publicly insured patients aged 13-64 years were identified. The exposure was ≥1 initial prescription (dispensed opioid prescription within 3 days of the procedure). The association between the exposure and ≥1 overdose within 90 days of the procedure was evaluated using logistic regression. In the family analysis, procedures for privately insured patients in family plans were identified. The association between the exposure and ≥1 overdose in a family member within 90 days was evaluated using logistic regression. In both analyses, the average marginal effect of the exposure was calculated, representing the change in the probability of the outcome if all versus if no procedures were associated with ≥1 initial prescription.

resultsThe patient analysis included 8,544,098 procedures. When ≥1 initial prescription did and did not occur, the 90-day risk of overdose was 5.8 versus 2.2 per 10,000 procedures (average marginal effect=1.5, 95% CI=1.2, 1.8). The family analysis included 3,461,469 procedures. When ≥1 initial prescription did and did not occur, the 90-day risk of overdose in a family member was 1.7 versus 1.0 per 10,000 procedures (average marginal effect=0.4, 95% CI=0.1, 0.7).

conclusionsFindings further highlight the importance of avoiding unnecessary dental opioid prescribing.

Indexed as

Analgesics, OpioidDrug OverdoseDrug PrescriptionsHumansMedicaidPractice Patterns, Physicians'PrescriptionsRetrospective StudiesUnited StatesAnalgesics, Opioid

Identifiers

PMID33975766
PMCPMC8319034
OpenAlexW3158686413

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.