Evidence map›Paper›PMID 33975604›Full record

ArticleWorld journal of surgical oncology2021

CT imaging-based machine learning model: a potential modality for predicting low-risk and high-risk groups of thymoma: "Impact of surgical modality choice".

Ayten Kayi Cangir, Kaan Orhan, Yusuf Kahya, Hilal Özakıncı, Betül Bahar Kazak, Buse Mine Konuk Balcı, Duru Karasoy, Çağlar Uzun

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. CT radiomics and human-machine hybrid system for differentiating mediastinal lymphomas from thymic epithelial tumors.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ayten Kayi CangirDepartment of Thoracic Surgery, İbn-i Sina Hospital, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey. cangir@medicine.ankara.edu.tr.ORCID http://orcid.org/0000-0002-2052-1642
Kaan OrhanAnkara University Medical Design Application and Research Center (MEDITAM), 06100, Sıhhiye, Ankara, Turkey.
Yusuf KahyaDepartment of Thoracic Surgery, İbn-i Sina Hospital, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey.
Hilal ÖzakıncıDepartment of Pathology, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey.
Betül Bahar KazakDepartment of Thoracic Surgery, İbn-i Sina Hospital, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey.
Buse Mine Konuk BalcıDepartment of Thoracic Surgery, İbn-i Sina Hospital, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey.
Duru KarasoyDepartment of Statistics, Hacettepe University Faculty of Science, 06800, Beytepe, Ankara, Turkey.
Çağlar UzunDepartment of Radiology, Ankara University Faculty of Medicine, 06100, Sıhhiye, Ankara, Turkey.
Ankara University · TRHacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRadiomics methods are used to analyze various medical images, including computed tomography (CT), magnetic resonance, and positron emission tomography to provide information regarding the diagnosis, patient outcome, tumor phenotype, and the gene-protein signatures of various diseases. In low-risk group, complete surgical resection is typically sufficient, whereas in high-risk thymoma, adjuvant therapy is usually required. Therefore, it is important to distinguish between both. This study evaluated the CT radiomics features of thymomas to discriminate between low- and high-risk thymoma groups. MATERIALS AND

methodsIn total, 83 patients with thymoma were included in this study between 2004 and 2019. We used the Radcloud platform (Huiying Medical Technology Co., Ltd.) to manage the imaging and clinical data and perform the radiomics statistical analysis. The training and validation datasets were separated by a random method with a ratio of 2:8 and 502 random seeds. The histopathological diagnosis was noted from the pathology report.

resultsFour machine-learning radiomics features were identified to differentiate a low-risk thymoma group from a high-risk thymoma group. The radiomics feature names were Energy, Zone Entropy, Long Run Low Gray Level Emphasis, and Large Dependence Low Gray Level Emphasis.

conclusionsThe results demonstrated that a machine-learning model and a multilayer perceptron classifier analysis can be used on CT images to predict low- and high-risk thymomas. This combination could be a useful preoperative method to determine the surgical approach for thymoma.

Indexed as

ThymomaThymus NeoplasmsHumansMachine LearningPrognosisROC CurveTomography, X-Ray ComputedDiagnostic toolMachine learningMinimally invasive surgeryRadiomicsThymoma

Identifiers

PMID33975604
PMCPMC8114494
OpenAlexW3120537376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.