Evidence map›Paper›PMID 33975560›Full record

ArticleBMC ophthalmology2021

Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow-up.

Waleed Alsarhani, Saeed Alshahrani, Mahmood Showail, Nawaf Alhabdan, Osama Alsumari, Abdullah Almalki, Abdulaziz Alsarhani, Adel Alluhaidan, Bader Alqahtani

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Applications of Mitomycin C in Cornea and External Disease.Turkish journal of ophthalmology · 2023
    Review
  10. Article
  11. Evaluating the Efficacy and Safety of Different Pterygium Surgeries: A Review of the Literature.International journal of environmental research and public health · 2022
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Waleed AlsarhaniDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada. WAlsarhani@gmail.com.
Saeed AlshahraniCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Mahmood ShowailDepartment of Ophthalmology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Nawaf AlhabdanCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Osama AlsumariCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Abdullah AlmalkiCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Abdulaziz AlsarhaniCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Adel AlluhaidanDepartment of Ophthalmology, Ministry of the National Guard - Health Affairs, Riyadh, Saudi Arabia.
Bader AlqahtaniDepartment of Ophthalmology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
King Saud bin Abdulaziz University for Health Sciences · SAKing Abdulaziz University · SAKing Abdullah International Medical Research Center · SAKing Saud University · SAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study described the clinical features of patients with pterygium and analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting combined with intraoperative mitomycin C, and amniotic membrane grafting.

methodsA retrospective cohort study of primary pterygium was conducted between January 2017 and February 2020. Factors associated with pterygium severity and recurrence were analyzed by univariate analysis and logistic regression models.

resultsThe study included 292 patients with an average age of 53.3 ± 14.1 years, while the number of operated cases was 94. Pterygia involving the cornea were observed in 55 % of the cases. The overall rate of recurrence for the three procedures was 17 %. The average time of recurrence was 14.2 ± 11.9 months, with 37 % of the recurrences occurring after the first year. The only factor associated with a significant risk of recurrence was dry eye disease in both univariate (p = 0.021) and multivariate analysis (p = 0.026). The recurrence rates following conjunctival autografting with and without mitomycin C were 15.6 and 15.8 %, respectively. The recurrence rate following the amniotic membrane graft was  twofold (OR= 2.02)  (27 %) that following the conjunctival autograft (15.8 %).

conclusionsThe only factor associated with the recurrence of pterygium was dry eye disease. More than one-third of recurrences developed after the first year, which stresses the importance of a long follow-up. The recurrence rate in our study following conjunctival graft was slightly higher compared to the literature mainly due to differences in study areas, populations, and follow-up periods.

Indexed as

PterygiumAdultAgedConjunctivaFollow-Up StudiesHumansMiddle AgedMitomycinRecurrenceRetrospective StudiesSaudi ArabiaTransplantation, AutologousTreatment OutcomeMitomycinConjunctivaPterygiumRecurrence

Identifiers

PMID33975560
PMCPMC8111970
OpenAlexW3162904865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.