Evidence map›Paper›PMID 33975359›Full record

ArticlePlanta medica2021

Silica Gel-mediated Oxidation of Prenyl Motifs Generates Natural Product-Like Artifacts.

Yu Tang, J Brent Friesen, Dejan S Nikolić, David C Lankin, James B McAlpine, Shao-Nong Chen, Guido F Pauli

Abstract read
In one paragraph

Article in Planta medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu TangUIC/NIH Center for Botanical Dietary Supplements Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-1998-3521
J Brent FriesenCenter for Natural Product Technologies (CENAPT), Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0002-0739-9224
Dejan S NikolićUIC/NIH Center for Botanical Dietary Supplements Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-3569-8069
David C LankinUIC/NIH Center for Botanical Dietary Supplements Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-3166-5980
James B McAlpineCenter for Natural Product Technologies (CENAPT), Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-1696-8828
Shao-Nong ChenUIC/NIH Center for Botanical Dietary Supplements Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-0748-0863
Guido F PauliUIC/NIH Center for Botanical Dietary Supplements Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States.ORCID 0000-0003-1022-4326

Funding

Van Breemen: Project 3; Botanical Dietary Supplements - Metabolism and Safety in Women (Van Breemen)P50AT000155 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 1999 to 2019
$30.4M
Center for Natural Product Technologies at UIC (CeNAPT)U41AT008706 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 2015 to 2019
$1.5M
NCCIH NIH HHS P50 AT000155NCCIH NIH HHS U41 AT008706P50AT000155 National Center for Complementary and Integrative HealthU41AT8706 National Center for Complementary and Integrative Health
6 · The paper itself

Abstract

Prenyl moieties are commonly encountered in the natural products of terpenoid and mixed biosynthetic origin. The reactivity of unsaturated prenyl motifs is less recognized and shown here to affect the acyclic

Indexed as

Biological ProductsArtifactsNeopreneSilica GelBiological ProductsNeopreneprenylSilica Gel

Identifiers

PMID33975359
PMCPMC8867998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.