Evidence map›Paper›PMID 33974992›Full record

ReviewThe Canadian journal of cardiology2021

Patient-Reported Outcomes in Cardiovascular Trials.

Ruth Masterson Creber, Cristiano Spadaccio, Arnaldo Dimagli, Annie Myers, Brittany Taylor, Stephen Fremes

Open access · greenAbstract readReview
In one paragraph

Review in The Canadian journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Minimal clinically important differences in patient-reported outcomes after coronary artery bypass surgery in the arterial revascularization trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Trial
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  8. Observational
  9. Review
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  11. Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients.Journal of cardiovascular translational research · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Ruth Masterson CreberDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA. Electronic address: rmc2009@med.cornell.edu.
Cristiano SpadaccioInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Arnaldo DimagliBristol Heart Institute, University of Bristol, Bristol, United Kingdom.
Annie MyersDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Brittany TaylorSchool of Nursing, Columbia University, New York, New York, USA.
Stephen FremesSunnybrook Health Science, University of Toronto, Toronto, Ontario, Canada.
Cornell University · USColumbia University · USSunnybrook Health Science Centre · CAUniversity of Bristol · GBUniversity of Glasgow · GB

Funding

Reducing Health Disparities Through Informatics - Genomics SupplementT32NR007969 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUZANNE BAKKEN, Rebecca Schnall · 2002 to 2026
$7.9M
Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)R01HL152021 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAUDINO, MARIO FL, MASTERSON CREBER, RUTH MARIE · 2020 to 2024
$4.1M
Should we return patient reported outcomes to human subjects participants?-exploring ethical obligationsR00NR016275 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASTERSON CREBER, RUTH MARIE · 2018 to 2020
$896k
mHealth for Heart Failure Symptom MonitoringK99NR016275 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MASTERSON CREBER, RUTH MARIE · 2016 to 2017
$182k
NHLBI NIH HHS R01 HL152021NINR NIH HHS K99 NR016275NINR NIH HHS R00 NR016275NINR NIH HHS T32 NR007969
6 · The paper itself

Abstract

Patient-reported outcomes (PROs) are reports of a person's health status that provide a global perspective of patient well-being. PROs can be classified into 4 primary domains: global, mental, physical, and social health. In this descriptive review, we focus on how PROs can be used in cardiac clinical trials, with an emphasis on cardiac surgical trials for patients with coronary heart disease and heart failure. We also highlight ongoing challenges and provide specific suggestions and novel opportunities to advance cardiac clinical trials. Current challenges include the long-term measurement of PROs in clinical trials beyond 1 year, inconsistency in the choice of the outcome measures among studies, and the lack of measurement of PROs across multiple domains. Opportunities for advancement include measuring PROs using consumer health informatics tools, including returning information back to participants in formats that they can understand using visualization. Future opportunities include quantifying cohort-specific minimal clinically important differences for PROs.

Indexed as

Clinical Trials as TopicPatient Reported Outcome MeasuresConsumer Health InformaticsCoronary DiseaseHeart FailureHumansMyocardial Revascularization

Identifiers

PMID33974992
PMCPMC8487900
OpenAlexW3161909122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.