ArticleCryobiology2021
Natural deep eutectic systems, an emerging class of cryoprotectant agents.
Article in Cryobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Formulation of Innovative Spirit Varnishes Using Eutectic Systems as Alternative Solvents.ChemSusChem · 2026Article
- Evaluation of Deep Eutectic Solvents for Cryopreservation of the Fish PathogenMethods and protocols · 2026Article
- Eutectogels: Recent Advances, Design Strategies, and Emerging Applications in Biotechnology.Gels (Basel, Switzerland) · 2025Review
- Incorporation of a Natural Deep Eutectic Solvent-Based System as a Cryoprotectant in Solid Lipid Nanoparticles: Advancing toward Industrial Scalability.ACS nanoscience Au · 2025Article
- Molecular weight-based profiling of sperm proteins and their association with semen quality in Kokok Balenggek roosters.Journal of advanced veterinary and animal research · 2025Article
- Innovations in Platelet Cryopreservation: Evaluation of DMSO-Free Controlled-Rate Freezing and the Role of a Deep Eutectic Solvent as an Additional Cryoprotective Agent.International journal of molecular sciences · 2025Article
- Application of Hansen solubility parameters in the eutectic mixtures: difference between empirical and semi-empirical models.Scientific reports · 2025Article
- Investigation of oligomeric proanthocyanidins extracted from Rhodiolae Crenulatae Radix et Rhizomes using deep eutectic solvents and identified via data-dependent acquisition mass-spectroscopy.Journal of pharmaceutical analysis · 2024Article
- Pharmaceutical applications of therapeutic deep eutectic systems (THEDES) in maximising drug delivery.Heliyon · 2024Review
- From Nature to Innovation: The Uncharted Potential of Natural Deep Eutectic Solvents.Molecules (Basel, Switzerland) · 2023Review
- Cryoprotective Effect of NADES on Frozen-Thawed Mirror Carp Surimi in Terms of Oxidative Denaturation, Structural Properties, and Thermal Stability of Myofibrillar Proteins.Foods (Basel, Switzerland) · 2023Article
- Using Natural Deep Eutectic Systems as Alternative Media for Ocular Applications.Pharmaceutics · 2023Article
- Research Progress on the Preparation and Action Mechanism of Natural Deep Eutectic Solvents and Their Application in Food.Foods (Basel, Switzerland) · 2022Review
- Assessing the Influence of Betaine-Based Natural Deep Eutectic Systems on Horseradish Peroxidase.ACS sustainable chemistry & engineering · 2022Article
- Natural Cryoprotective and Cytoprotective Agents in Cryopreservation: A Focus on Melatonin.Molecules (Basel, Switzerland) · 2022Review
- Use of natural deep eutectic systems as new cryoprotectant agents in the vitrification of mammalian cells.Scientific reports · 2022Article
- Efficient Citrus (ACS omega · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work aimed at evaluating the potential of using natural deep eutectic systems (NADES) as cryoprotectant agents (CPAs). Several combinations between natural primary metabolites that have been identified in animals that live in extreme cold climates were prepared. All systems showed very little cytoxicity towards L929 cells at concentrations high as 1-2 M. Moreover, this cell line was highly tolerant to 10% (w/v) of NADES when compared to Me
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.