Evidence map›Paper›PMID 33974633›Full record

ArticlePloS one2021

Genetic association study between TAB2 polymorphisms and noise-induced-hearing-loss in a Han Chinese population.

Guangzhi Yang, Boshen Wang, Dawei Sun, Huimin Wang, Mengyao Chen, Hao Chen, Baoli Zhu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. [Research progress in genetics of noise-induced hearing loss].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Guangzhi YangSchool of Public Health, Southeast University, Nanjing, Jiangsu, China.ORCID 0000-0003-4024-2381
Boshen WangSchool of Public Health, Southeast University, Nanjing, Jiangsu, China.
Dawei SunSchool of Public Health, Southeast University, Nanjing, Jiangsu, China.
Huimin WangSchool of Public Health, Southeast University, Nanjing, Jiangsu, China.
Mengyao ChenSchool of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
Hao ChenSchool of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
Baoli ZhuSchool of Public Health, Southeast University, Nanjing, Jiangsu, China.
Southeast University · CNJiangsu Provincial Center for Disease Control and Prevention · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noise-induced-hearing-loss(NIHL) is a common occupational disease caused by various environmental and biological factors. To investigate the association between TAB2 and the susceptibility of NIHL of people exposed to occupational environments, a genetic association study was performed on selected companies with 588 cases and 537 healthy control subjects. Five selected single nucleotide polymorphisms (SNPs) in TAB2,incoluding rs2744434, rs521845, rs652921, rs7896, rs9485372, were genotyped after a collection of DNA samples. Evident differences in participants between the case group and the control group reveals the result that people with the TAB2 has a high probability of getting NIHL. The results show that rs521845 is deeply associated with the risk of NIHL and is available for the diagnosis in the future.

Indexed as

Noise, OccupationalAdaptor Proteins, Signal TransducingAdolescentAdultAgedAged, 80 and overAsian PeopleChinaFemaleGenetic Association StudiesHearing Loss, Noise-InducedHumansMaleMiddle AgedOccupational DiseasesPolymorphism, Single NucleotideAdaptor Proteins, Signal TransducingTAB2 protein, human

Identifiers

PMID33974633
PMCPMC8112696
OpenAlexW3160941779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.