ArticleCurrent protocols2021
Overview of Chemotaxis Behavior Assays in Caenorhabditis elegans.
Article in Current protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- TAXISCAN, Optimizing throughput and behavioral depth in standardbioRxiv : the preprint server for biology · 2026Article
- Immobilization-free chemotaxis analysis reveals the novel behavioral mode of "leaving" inbioRxiv : the preprint server for biology · 2026Article
- Memsensing by surface ion migration within Debye length.Nature materials · 2026Article
- Dietary mycotoxin toxicity inAdvances in neurotoxicology · 2026Article
- Effect of Hong Huang Tang on memory enhancement and mitigation of microgravity-induced oxidative stress in C. elegans.Biogerontology · 2025Article
- Perspective on Interdisciplinary Approaches on Chemotaxis.Angewandte Chemie (International ed. in English) · 2025Review
- Leaf miRNAs of Withania somnifera Negatively Regulate the Aging-Associated Genes in C. elegans.Molecular neurobiology · 2025Article
- Curcumin enhances the anti-obesogenic activity of orlistat through SKN-1/NRF2-dependent regulation of nutrient metabolism in Caenorhabditis elegans.International journal of obesity (2005) · 2025Article
- Enhancing Reproducibility in Chemotaxis Assays for Caenorhabditis elegans.Current protocols · 2025Article
- Improved particle filter algorithm combined with culture algorithm for collision Caenorhabditis elegans tracking.Scientific reports · 2025Article
- A simple yet reliable assay for chemotaxis inmicroPublication biology · 2025Article
- The chemotactic response of Caenorhabditis elegans represents a promising tool for the early detection of cancer.Discover oncology · 2024Article
- Assessment of azithromycin-induced toxicity inToxicology reports · 2024Article
- Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3.Nature communications · 2024Article
- Timut Pepper Extract Slows Age-Dependent Decline of Mobility and Collagen Loss and Promotes Longevity.Nutrients · 2024Article
- An efficient behavioral screening platform classifies natural products and other chemical cues according to their chemosensory valence inbioRxiv : the preprint server for biology · 2024Article
- Worm-Based Diagnosis Combining Microfluidics toward Early Cancer Screening.Micromachines · 2024Review
- An automatic measurement method for the response of Caenorhabditis elegans to chemicals.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Maackiain Mimics Caloric Restriction throughInternational journal of molecular sciences · 2023Article
- An Undergraduate Laboratory Series UsingJournal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Environmental pollution related to anthropogenic pressures, and the associated repercussions on public health, represent a worldwide problem. Thus, the study of the effects that environmental contaminants can pose to natural ecosystems and human health is of vital importance. Laboratory model organisms such as Caenorhabditis elegans have played a significant role in clarifying multilevel effects of those agents. Although the evaluation of contaminant effects at the behavioral level of organisms is an emerging approach in ecotoxicology, studies assessing chemotaxis behavior in C. elegans within the ecotoxicological research context are still scarce. Chemotaxis studies in C. elegans have contributed to the understanding of both the neuronal mechanisms involved in the behavioral effects triggered by environmental cues and the impact of contaminants on natural ecosystems. Its compact and well-characterized nervous system, as well as the availability of transgenic strains and molecular tools, allows a detailed examination of behavioral, molecular, and genetic chemosensation mechanisms. This overview provides a summary and general comparison of methods used to measure chemotaxis behavior in C. elegans, with the aim of helping researchers select the most suitable approach in their chemotaxis studies. We compare methods based on the type of chemical tested, advantages and drawbacks of the different approaches, and specific experimental goals. Lastly, we hope to encourage the evaluation of C. elegans chemotaxis behavior in ecotoxicology studies, as well as its potential integration in standardized protocols assessing environmental quality. © 2021 Wiley Periodicals LLC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.