Evidence map›Paper›PMID 33974219›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

The handgrip strength and risk of depressive symptoms: a meta-analysis of prospective cohort studies.

Xiuxia Huang, Jun Ma, Yuting Ying, Kailiang Liu, Chunxia Jing, Guang Hao

Abstract readMeta-AnalysisReview
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In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Associations between muscle strength and mental health in older adults.Revista da Associacao Medica Brasileira (1992) · 2026
    Article
  2. Article
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  8. Hand grip strength and depression among rural older South Africans.Humanitas (Universitas Ahmad Dahlan. Fakultas Psikologi) · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiuxia Huang *Department of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China.
Jun Ma *Department of Clinical Medicine, Honghe Health Vocational College, Mengzi, China.
Yuting Ying *Department of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China.
Kailiang Liu *Department of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China.
Chunxia JingDepartment of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China. jcxphd@gmail.com.
Guang HaoDepartment of Epidemiology, School of Medicine, Jinan University, 601 West Huangpu Road, Guangzhou, 510632, Guangdong, China. haoguang2015@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany studies have investigated the association between handgrip strength (HGS) and depressive symptoms, but the conclusion remain controversial. We performed a meta-analysis to evaluate the longitudinal association between HGS and risk of depressive symptoms.

methodsPubMed, PSYCINFO and EMBASE databases were searched for eligible publications up to April 2020. Pooled relative risks (RRs) with 95% confidence intervals were calculated using random-effects model. Publication bias was estimated using Egger's test and the funnel plot. Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of eligible studies.

resultsThe present meta-analysis included 8 cohort studies with 30,727 participants. Overall, higher HGS was related to a decreased risk of depressive symptoms: the pooled risk ratio (RR) of 0.74 [95% confidence intervals (CI) 0.65-0.85] with a moderate heterogeneity (I

conclusionsLower HGS was associated with an increased risk of depressive symptoms. Further studies are needed to confirm these findings and to investigate the sex differences.

Indexed as

DepressionHand StrengthCohort StudiesFemaleHumansMaleProspective StudiesQuality of LifeCohort studyDepressive symptomsHandgrip strengthMeta-analysis

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.