Evidence map›Paper›PMID 33974186›Full record

ArticleDigestive diseases and sciences2022

Drivers of Variation in Diagnosis and Management of Eosinophilic Esophagitis: A Survey of Pediatric Gastroenterologists.

Talya L Miller, Arti D Desai, Michelle M Garrison, Dale Lee, Amanda Muir, K Casey Lion

Abstract read
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. What patients with eosinophilic esophagitis may not share with their providers: a qualitative assessment of online health communities.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Talya L MillerDepartment of Pediatrics, University of North Carolina, 101 Manning Drive, N.C. Children's Hospital, Ground Floor, Chapel Hill, NC, 27514, USA. talya.lepow.miller@gmail.com.
Arti D DesaiDepartment of Pediatrics, University of Washington/Seattle Children's Hospital, 4800 Sand Point Way NE, OB.9.620.1-Gastroenterology and Hepatology, Seattle, WA, 98105, USA.
Michelle M GarrisonSeattle Children's Research Institute, M/S CS8-6, 2001 Eighth Ave, PO BOX 5371, Seattle, WA, 98121, USA.
Dale LeeDepartment of Pediatrics, University of Washington/Seattle Children's Hospital, 4800 Sand Point Way NE, OB.9.620.1-Gastroenterology and Hepatology, Seattle, WA, 98105, USA.
Amanda MuirDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, 34th and Civic Center Boulevard, Philadelphia, PA, 19104, USA.
K Casey LionDepartment of Pediatrics, University of Washington/Seattle Children's Hospital, 4800 Sand Point Way NE, OB.9.620.1-Gastroenterology and Hepatology, Seattle, WA, 98105, USA.
University of Washington · USPhiladelphia University · USSeattle Children's Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Web-based Care Plans for Children with Medical ComplexityK08HS024299 · AHRQ · SEATTLE CHILDREN'S HOSPITAL · PI DESAI, ARTI D · 2015 to 2019
$741k
AHRQ HHS K08 HS024299NCATS NIH HHS UL1 TR002319
6 · The paper itself

Abstract

backgroundWidespread variation in the diagnosis and treatment of eosinophilic esophagitis (EoE) has previously been reported among adult gastroenterologists; however, variation in EoE practice in among pediatric populations is poorly characterized. The study objectives were to describe guideline adherence and understand reasons for variation in EoE practice among pediatric gastroenterologists following publication of the updated 2018 international EoE guidelines.

methodsWe developed and administered a 28-item survey to pediatric gastroenterologists via an email listserv using the PEDGI Bulletin Board from 03/2019 to 04/2019. The survey was developed using evidence-based review, expert validation, and cognitive interviews. Survey domains included respondent knowledge of and adherence to published guidelines, diagnostic and management approach and rationale, and participant demographics. Analysis included descriptive statistics and tests for association.

resultsA total of 288 pediatric gastroenterologists completed the survey, most of whom practiced in an academic center (73%). More than half (63%) reported knowledge of the 2018 updated guidelines; however, only 52% agreed with them and 50% reported adherence. Respondents who reported not agreeing with updated guidelines cited concerns regarding increasing number of endoscopies (72%), misdiagnosing eosinophilia from reflux (56%), and insufficient data (23%). The most common drivers of decision making with respect to therapy choice were patient/family preference, evidence/guidelines, and symptom burden.

conclusionsMany physicians are not adherent to current guidelines for reasons which include lack of knowledge of updated guidelines and concern regarding the strength of the supporting evidence. This study elucidates several areas to enhance education regarding these guidelines to promote widespread adherence.

Indexed as

Eosinophilic EsophagitisGastroenterologistsAdultChildEnteritisEosinophiliaGastritisGuideline AdherenceHumansSurveys and QuestionnairesEosinophilic esophagitisGuideline adherencePediatricPractice patterns

Identifiers

PMID33974186
OpenAlexW3160295569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.