Evidence map›Paper›PMID 33974163›Full record

ArticleApoptosis : an international journal on programmed cell death2021

LncRNA FGD5-AS1 promotes the malignant phenotypes of ovarian cancer cells via targeting miR-142-5p.

Zhang Aichen, Wang Kun, Sun Xiaochun, Tong Lingling

Abstract read
PubMed Publisher
In one paragraph

Article in Apoptosis : an international journal on programmed cell death, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  12. PD-L1: expression regulation.Blood science (Baltimore, Md.) · 2023
    Review
  13. Article
  14. The Features of Immune Checkpoint Gene Regulation by microRNA in Cancer.International journal of molecular sciences · 2022
    Review
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  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhang AichenDepartment of Obstetrics and Gynecology, The Third Hospital of Jilin University, 126th Xiantai Street, Changchun, 130021, Jilin, China.
Wang KunDepartment of Obstetrics and Gynecology, The Third Hospital of Jilin University, 126th Xiantai Street, Changchun, 130021, Jilin, China.
Sun XiaochunDepartment of Obstetrics and Gynecology, The Third Hospital of Jilin University, 126th Xiantai Street, Changchun, 130021, Jilin, China. xcsun@jlu.edu.cn.
Tong LinglingDepartment of Obstetrics and Gynecology, The Third Hospital of Jilin University, 126th Xiantai Street, Changchun, 130021, Jilin, China. tongll16@mails.jlu.edu.cn.ORCID http://orcid.org/0000-0001-7564-2559
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been reported to participate in regulating gene expression and are related to tumor progression. FGD5 antisense RNA 1 (FGD5-AS1) facilitates the progression of various tumors. However, the expression and function of FGD5-AS1 in ovarian cancer (OC) and its mechanism of action are not yet clear. Real-time polymerase chain reaction (RT-PCR) was employed to explore the expression levels of FGD5-AS1 and miR-142-5p in OC. The relationship between the expression of FGD5-AS1 and clinicopathological indicators of OC patients was analyzed by χ

Indexed as

AnimalsB7-H1 AntigenCarcinogenesisCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticGuanine Nucleotide Exchange FactorsHumansMiceMicroRNAsMiddle AgedOvarian NeoplasmsRNA, AntisenseRNA, Long NoncodingB7-H1 AntigenCD274 protein, humanFGD5 protein, humanGuanine Nucleotide Exchange FactorsMicroRNAsMIRN142 microRNA, humanRNA, AntisenseRNA, Long NoncodingFGD5-AS1MiR-142-5pOCPD-L1

Identifiers

PMID33974163
OpenAlexW3162922968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.