ArticlePediatric radiology2021
Practical approach for the diagnosis of biliary atresia on imaging, part 2: magnetic resonance cholecystopancreatography, hepatobiliary scintigraphy, percutaneous cholecysto-cholangiography, endoscopic retrograde cholangiopancreatography, percutaneous liver biopsy, risk scores and decisional flowchart.
Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- The diagnostic performance of ultrasound elastography for biliary atresia: A meta-analysis.Frontiers in public health · 2022Pooled it
- Diagnostic and management guidelines for biliary atresia in 2025.Hepatobiliary surgery and nutrition · 2026Review
- Early Prediction of Biliary Atresia Using Combi-Elastography in Infants ≤ 60 Days of Age.Diagnostics (Basel, Switzerland) · 2026Article
- A strategy to identify biliary atresia efficiently: A perspective from a Texas center.World journal of pediatric surgery · 2026Review
- Endoscopic retrograde cholangiopancreatography as a diagnostic key tool for biliary atresia: feasibility, safety and accuracy in neonates with cholestatic liver disease.European journal of pediatrics · 2025Article
- Intervention in the Native and Transplant Liver in Children: An Update.Cardiovascular and interventional radiology · 2025Review
- Booster administration of Tc-99m PMT for delayed static imaging in patients with biliary atresia.Annals of nuclear medicine · 2024Article
- Improving the Outcome of Biliary Atresia: All Hands on Deck.Indian journal of pediatrics · 2024Article
- Value of gallbladder length-to-width ratio for diagnosis of biliary atresia by correlation with age.Updates in surgery · 2023Article
- Anomalies of the fetal gallbladder: pre-and postnatal correlations.Pediatric radiology · 2023Article
- A multi-disciplinary, comprehensive approach to management of children with heterotaxy.Orphanet journal of rare diseases · 2022Review
- [Diagnostic Imaging of Biliary Atresia].Journal of the Korean Society of Radiology · 2022Review
- Biliary atresia and congenital disorders of the extrahepatic bile ducts.World journal of gastrointestinal pharmacology and therapeutics · 2022Review
- Ultrasound elastography in the diagnosis of biliary atresia in pediatric surgery: a systematic review and meta-analysis of diagnostic test.Translational pediatrics · 2022Article
- Ultrasound for the Diagnosis of Biliary Atresia: From Conventional Ultrasound to Artificial Intelligence.Diagnostics (Basel, Switzerland) · 2021Review
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Authors and funding
19 authors at 19 institutions in 12 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aim to present a practical approach to imaging in suspected biliary atresia, an inflammatory cholangiopathy of infancy resulting in progressive fibrosis and obliteration of extrahepatic and intrahepatic bile ducts. Left untreated or with failure of the Kasai procedure, biliary atresia progresses to biliary cirrhosis, end-stage liver failure and death within the first years of life. Differentiating biliary atresia from other nonsurgical causes of neonatal cholestasis is difficult as there is no single method for diagnosing biliary atresia and clinical, laboratory and imaging features of this disease overlap with those of other causes of neonatal cholestasis. In this second part, we discuss the roles of magnetic resonance (MR) cholecystopancreatography, hepatobiliary scintigraphy, percutaneous biopsy and percutaneous cholecysto-cholangiography. Among imaging techniques, ultrasound (US) signs have a high specificity, although a normal US examination does not rule out biliary atresia. Other imaging techniques with direct opacification of the biliary tree combined with percutaneous liver biopsy have roles in equivocal cases. MR cholecystopancreatography and hepatobiliary scintigraphy are not useful for the diagnosis of biliary atresia. We propose a decisional flowchart for biliary atresia diagnosis based on US signs, including elastography, percutaneous cholecysto-cholangiography or endoscopic retrograde cholangiopancreatography and liver biopsy.
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