ArticleThe Journal of clinical endocrinology and metabolism2021
Increasing Incidence of Primary Aldosteronism in Western Sweden During 3 Decades - Yet An Underdiagnosed Disorder.
Article in The Journal of clinical endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Emerging methods for subtype differentiation in primary aldosteronism.Journal of internal medicine · 2026Review
- Approach to the Patient With Primary Aldosteronism: Role of Molecular Imaging.The Journal of clinical endocrinology and metabolism · 2025Review
- Screening and Diagnosis Trends for Primary Aldosteronism: A Longitudinal Nationwide Cohort Study of 7.8 Million People.medRxiv : the preprint server for health sciences · 2025Article
- Article
- A global real-world study assessing total time to adrenalectomy in primary aldosteronism.European journal of endocrinology · 2025Article
- Serum microRNAs as peripheral markers of primary aldosteronism.Frontiers in endocrinology · 2025Article
- Screening for primary aldosteronism in 1,181 Swedish primary care patients with hypertension.Frontiers in endocrinology · 2025Article
- Hip fractures in patients with primary aldosteronism - a Swedish nationwide study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- Temporal trends in clinical features of patients with primary aldosteronism over 20 years.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Health Care Challenges in the Management of Primary Aldosteronism in Southeast Asia.The Journal of clinical endocrinology and metabolism · 2024Article
- Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism.Frontiers in endocrinology · 2023Article
- Specialty grand challenge in adrenal endocrinology.Frontiers in endocrinology · 2023Article
- Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness.Clinical endocrinology · 2022Article
- Primary aldosteronism - a multidimensional syndrome.Nature reviews. Endocrinology · 2022Review
- Clinical Translationality ofInternational journal of molecular sciences · 2022Review
- Response to Letter to the Editor From Singhania et al.: "Increasing Incidence of Primary Aldosteronism in Western Sweden During 3 Decades - Yet an Underdiagnosed Disorder".The Journal of clinical endocrinology and metabolism · 2022Article
- Illness perspectives in patients with primary aldosteronism.PloS one · 2022Article
- The incidence of insulinoma in Western Sweden between 2002 and 2019.Annals of gastroenterologyArticle
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPrimary aldosteronism (PA) is the most common cause of secondary hypertension. Yet, the incidence of PA in the general population has not been studied.
objectiveTo estimate the incidence of PA in the general population. DESIGN AND
methodsPatients who had received a diagnostic code for PA between 1987 and 2016 were identified in the Swedish National Patient Registry. Assessment of clinical and biochemical data was used to validate the diagnosis. The annual incidence of PA was calculated by using the number of inhabitants in the Västra Götaland County as a reference.
resultsOf 570 identified patients, 473 (83%) had confirmed PA. Eligible for the incidence analysis were 416 patients, 248 (60%) men and 168 (40%) women, diagnosed with PA between 1987 and 2016. The mean (± standard deviation) age at diagnosis was 56 ± 12 years. The median (interquartile range) annual incidence was 2 (1-2) cases per million between 1987 and 1996, 6 (4-9) cases per million between 1997 and 2006 and 17 (12-24) cases per million between 2007 and 2016. At the end of the study (December 31, 2016), 386 patients with confirmed PA were alive and living in the Västra Götaland County, giving a prevalence of 231 cases per million (0.022%).
conclusionsDespite increasing incidence, the proportion of patients identified with PA is lower than expected. Given the serious consequences of untreated PA, the noticeably low prevalence at the end of the study stresses the need to increase the awareness of PA among health care providers.
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