Evidence map›Paper›PMID 33973484›Full record

Observational studyThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2022

A Preliminary Study of Anatomical Changes Following the Use of a Pedicled Buccal Fat Pad Flap During Primary Palatoplasty.

Katelyn J Kotlarek, Michael S Jaskolka, Xiangming Fang, Charles Ellis, Silvia S Blemker, Bruce Horswell, Paul Kloostra, Jamie L Perry

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Impact of Muscular Asymmetry on Velopharyngeal Function in Children with Craniofacial Microsomia: A Pilot Study.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  3. Observational
  4. Review
  5. Growth and Symmetry of the Levator Veli Palatini Muscle Within the First Two Years of Life.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  6. Article
  7. Establishing a Clinical Protocol for Velopharyngeal MRI and Interpreting Imaging Findings.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Katelyn J KotlarekDivision of Communication Disorders, University of Wyoming, Laramie, WY, USA.ORCID 0000-0001-5974-3309
Michael S JaskolkaNew Hanover Regional Medical Center, Wilmington, NC, USA.
Xiangming FangDepartment of Biostatistics, East Carolina University, Greenville, NC, USA.
Charles EllisDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.
Silvia S BlemkerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Bruce HorswellIndiana University Hospital, Indianapolis, IN, USA.
Paul KloostraCharleston Area Medical Center, Charleston, WV, USA.
Jamie L PerryDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-7866-9159
East Carolina University · USCharleston Area Medical Center · USIndiana University Hospital · USNew Hanover Regional Medical Center · USUniversity of Virginia · USUniversity of Wyoming · US

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI David S Fay · 2012 to 2026
$56.8M
MRI-Based Modeling to Understand Anatomical Basis of Velopharyngeal DysfuntionR21DC014570 · NIDCD · UNIVERSITY OF VIRGINIA · PI BLEMKER, SILVIA SALINAS, PERRY, JAMIE L · 2015 to 2016
$409k
Investigation of Anatomical and Physiological Changes Following the Use of a Pedicled Buccal Fat Pad Graft During Primary PalatoplastyF31DE027878 · NIDCR · EAST CAROLINA UNIVERSITY · PI KOTLAREK, KATELYN JOY · 2018 to 2019
$48k
NIDCD NIH HHS R21 DC014570NIDCR NIH HHS F31 DE027878NIGMS NIH HHS P20 GM103432
6 · The paper itself

Abstract

objectiveThe purpose of this study was to examine the surgical impact of the pedicled buccal fat pad (BFP) flap on the levator veli palatini (LVP) muscle and surrounding velopharyngeal (VP) anatomy following primary palatoplasty using magnetic resonance imaging (MRI).

designObservational, prospective.

settingMRI studies were completed at 3 different facilities. All participants with BFP flap were operated on by the same surgeon.

participantsFive pediatric participants with cleft palate with or without cleft lip (CP±L) who underwent primary palatoplasty with BFP flap placement. Comparison groups consisted of 10 participants: 5 with CP±L who did not receive the BFP flap and 5 healthy controls.

interventionsAll participants underwent nonsedated MRI 2 to 5 years postoperatively. MAIN OUTCOMES AND MEASURES: Anatomical measures of the velopharynx and LVP among the 3 participant groups.

resultsMedian values were significantly different among groups for velar length (

conclusionsThis study provides preliminary support that the BFP flap creates a longer velum, with increased distance between the posterior hard palate and the LVP, and a larger effective VP ratio compared to traditional surgical techniques. Future research is needed to determine whether this procedure provides a more favorable mechanism for VP closure.

Indexed as

Cleft PalateVelopharyngeal InsufficiencyAdipose TissueChildHumansPalatal MusclesPalate, SoftProspective StudiesMRIoutcomespalatoplasty

Identifiers

PMID33973484
PMCPMC8581071
OpenAlexW3160654921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.