Evidence map›Paper›PMID 33973417›Full record

ArticleJournal of Zhejiang University. Science. B2021

Exosomes in bladder cancer: novel biomarkers and targets.

Hao Geng, Qingchen Zhou, Wenhao Guo, Ling Lu, Liangkuan Bi, Yi Wang, Jie Min, Dexin Yu, Zhaofeng Liang

Open access · greenAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hao GengDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Qingchen ZhouDepartment of Urology, the First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
Wenhao GuoJiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
Ling LuDepartment of Child Healthcare, Women and Children Health Hospital of Zhenjiang, Zhenjiang 212001, China.
Liangkuan BiDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Yi WangDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Jie MinDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China.
Dexin YuDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China. dxyu@ahmu.edu.cn.
Zhaofeng LiangJiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China. liangzhaofeng@ujs.edu.cn.
Anhui Medical University · CNJiangsu University · CNShenzhen Maternity and Child Healthcare Hospital · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are nanometer-sized vesicles that contain various types of biologically active components, including proteins, nucleic acids, carbohydrates, and lipids, which vary with the type and physiological state of the cell. In recent years, several studies have showed that exosomes can provide new non-invasive diagnostic and prognostic biomarkers in patients affected by cancers, including bladder cancer (BC), and the lipid bilayer membrane structure makes exosomes as promising delivery vehicles for therapeutic applications. Exosomes have the characteristics of high abundance, high stability, tissue specificity, and wide distribution in body fluids, and are secreted as various types by cells in different states, thereby possessing great potential as biomarkers for BC. Herein, we briefly summarize the functions and roles of exosomes in the occurrence and development of BC and the current progress of research on exosomes in BC, while focusing on potential clinical applications of the diagnosis, treatment, and prognosis of BC.

Indexed as

Biomarkers, TumorDisease ProgressionExosomesHumansUrinary Bladder NeoplasmsBiomarkers, TumorBiomarkerBladder cancerClinical applicationExosomeFunction

Identifiers

PMID33973417
PMCPMC8110466
OpenAlexW3163345721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.