ArticleThe plant genome2021
Differentially expressed microRNAs that target functional genes in mature soybean nodules.
Article in The plant genome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Leaf to Root: Harnessing leaf spectral signatures for non-destructive monitoring of soybean nodule traits.Plant phenomics (Washington, D.C.) · 2026Article
- Whole-genome sequencing reveals a possible molecular basis of sex determination in the dioecious wild yam Dioscorea tokoro.PLoS genetics · 2026Article
- Roles of microRNAs and histone modifications in enhancing stress tolerance in soybean and their applications in molecular breeding.Breeding science · 2025Article
- Transcriptomes of soybean roots and nodules inoculated with Sinorhizobium fredii with NopP and NopI variants.Scientific data · 2024Article
- Insights into the Early Steps of the Symbiotic Interaction between Soybean (Journal of agricultural and food chemistry · 2024Article
- The Biosynthesis Process of Small RNA and Its Pivotal Roles in Plant Development.International journal of molecular sciences · 2024Review
- Changes in epigenetic features in legumes under abiotic stresses.The plant genome · 2023Review
- Editorial: Metabolic adjustments and gene expression reprogramming for symbiotic nitrogen fixation in legume nodules, volume II.Frontiers in plant science · 2023Article
- Using the Knowledge of Post-transcriptional Regulations to Guide Gene Selections for Molecular Breeding in Soybean.Frontiers in plant science · 2022Review
- Roles of non-coding RNAs in the hormonal and nutritional regulation in nodulation and nitrogen fixation.Frontiers in plant science · 2022Review
- Differentially expressed microRNAs that target functional genes in mature soybean nodules.The plant genome · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are important regulators of biological functions in plants. To find out what roles miRNAs play in regulating symbiotic nitrogen fixation (SNF) in soybean [Glycine max (L.) Merr.], we identified high-confidence differentially expressed (DE) miRNAs from uninoculated roots (UR), rhizobium-inoculated roots (IR), and nodules (NODs) of soybean by robust small RNA sequencing (sRNA-seq). Based on their predicted target messenger RNAs (mRNAs), the expression profiles of some of these DE miRNAs could be linked to nodule functions. In particular, several miRNAs associated with nutrient transportation genes were differentially expressed in IRs and mature NODs. MiR399b, specifically, was highly induced in IRs and NODs, as well as by inorganic phosphate (Pi) starvation. In composite soybean plants overexpressing miR399b, PHOSPHATE2 (PHO2), a known target of miR399b that inhibits the activities of high-affinity Pi transporters, was strongly repressed. In addition, the overexpression of miR399b in the roots of transgenic composite plants significantly improved whole-plant Pi and ureide concentrations and the overall growth in terms of leaf node numbers and whole-plant dry weight. Our findings suggest that the induction of miR399b in NODs could enhance nitrogen fixation and soybean growth, possibly via improving Pi uptake to achieve a better Pi-nitrogen balance to promote SNF in nodules.
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Registered trials
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