Evidence map›Paper›PMID 33973355›Full record

ArticleJournal of the International AIDS Society2021

HIV risk and pre-exposure prophylaxis interest among women seeking post-abortion care in Kenya: a cross-sectional study.

Renee Heffron, Edinah Casmir, Linda Aswani, Kenneth Ngure, Benn Kwach, Vallery Ogello, Catherine Kiptinness, Faith Ambiyo, Njeri Wairimu, Ethel Ossome and 7 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Renee HeffronDepartment of Global Health, University of Washington, Seattle, USA.ORCID 0000-0001-6039-0352
Edinah CasmirPartners in Health and Research Development, Thika, Kenya.
Linda AswaniCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Kenneth NgureJomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.ORCID 0000-0002-8062-0933
Benn KwachCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Vallery OgelloCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Catherine KiptinnessPartners in Health and Research Development, Thika, Kenya.
Faith AmbiyoPartners in Health and Research Development, Thika, Kenya.
Njeri WairimuPartners in Health and Research Development, Thika, Kenya.
Ethel OssomeCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Hilda MachafuCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Yasaman ZiaDepartment of Global Health, University of Washington, Seattle, USA.ORCID 0000-0001-6049-3706
Dorothy ThomasDepartment of Global Health, University of Washington, Seattle, USA.
Caitlin ScovilleDepartment of Global Health, University of Washington, Seattle, USA.
Taryn BarkerChildren's Investment Fund Foundation, London, UK.
Elizabeth BukusiDepartment of Global Health, University of Washington, Seattle, USA.
Nelly MugoDepartment of Global Health, University of Washington, Seattle, USA.

Funding

INTERNATIONAL TRAINING GRANT IN EPIDEMIOLOGYD43TW000007 · FIC · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 1988 to 2012
$16.3M
Women and HIV: Translation of Research into Practice-WLHIV Post-Graduate Research FellowshipD43TW009783 · FIC · UNIVERSITY OF WASHINGTON · PI Elizabeth Anne BUKUSI, CAREY FARQUHAR · 2015 to 2026
$4.1M
FIC NIH HHS D43 TW000007FIC NIH HHS D43 TW009783
6 · The paper itself

Abstract

introductionPost-abortion clinics located in regions with high HIV burden may ideal locations to integrate counselling and delivery of HIV pre-exposure prophylaxis (PrEP), aligning with normative goals for integrated delivery of HIV and reproductive health care. The objective of this study was to gauge the degree to which Kenyan women seeking care for a pregnancy loss, including induced abortion, are at risk for HIV and whether women would welcome an introduction to PrEP prior to discharge from post-abortion care.

methodsWe conducted a mixed-methods study from August 2019 to February 2020 with women ages 15 to 30 recruited sequentially as they were accessing post-abortion care at public and private facilities in Thika and Kisumu, Kenya. Data collection was through a cross-sectional survey and laboratory testing for common sexually transmitted infections (N = 200), and in-depth interviews (N = 30). Descriptive statistics summarize PrEP knowledge and referrals and a multivariable log-link binomial model estimated correlates of receiving a referral for PrEP. Qualitative data were analysed using inductive and deductive approaches.

resultsAmong 200 HIV-negative women (median age 21.0, interquartile range 19.0 to 22.0), the prevalence of Chlamydia trachomatis was 18.2% and Neisseria gonorrhoeae was 2.0%. Half of the women scored ≥5 on a validated tool that would correspond to an expected HIV incidence of 9.5% per year. Approximately half (55.8%) of women were familiar with PrEP prior to the study and 33.3% received a referral from study staff to a clinic offering PrEP. In qualitative interviews, women expressed interest in accessing PrEP from the gynaecology ward that provided post-abortion care but they preferred alternative locations for PrEP refills.

conclusionsKenyan women accessing post-abortion care have substantial HIV risk and were favourable about the idea of receiving support to initiate PrEP as part of care offered during post-abortion care. These settings can be integrated into national PrEP programmes as locations providing PrEP referrals and initiation.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentAdultCross-Sectional StudiesFemaleHumansKenyaPregnancyYoung AdultAnti-HIV AgentsabortionHIV preventionKenyaPrEPyoung women

Identifiers

PMID33973355
PMCPMC8110894

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.