ArticlePituitary2021
Normative data for pituitary size and volume in the general population between 50 and 66 years.
Article in Pituitary, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Magnetic resonance imaging-based morphometric differences in the normal pituitary gland with functional and nonfunctional pituitary adenomas.Surgical neurology international · 2026Article
- Differential role of anterior and posterior pituitary lobes in healthy aging and perceived stress.Scientific reports · 2025Article
- Automated Segmentation of the Pituitary and Pineal Glands.Human brain mapping · 2025Article
- Morphometric study of the pituitary gland and stalk with emphasis on lifestyle factors.Pituitary · 2025Article
- Normative Data for The Dimensions and Volume of Pituitary Gland in The General Population Undergoing Magnetic Resonance Imaging Under a Tertiary Care Center: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- The Influence of Pituitary Morphology on the Occurrence of Hormonal Disorders in Patients with Empty Sella or Partial Empty Sella.Biomedicines · 2025Article
- Idiopathic hyperprolactinemia-associated hypogonadism in men presenting with normal testosterone levels.PloS one · 2025Article
- Assessing the Diagnostic Performance of Automated Pituitary Gland Volume Measurement for Idiopathic Central Precocious Puberty.Journal of clinical medicine · 2024Article
- Sex chromosomes and hormones independently influence healthy brain development but act similarly after cranial radiation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A pituitary gland squeezed upward by intrasellar kissing carotid arteries: Mimicking a pituitary microadenoma.Surgical neurology international · 2024Article
- deepPGSegNet: MRI-based pituitary gland segmentation using deep learning.Frontiers in endocrinology · 2024Article
- Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study.International journal of obesity (2005) · 2023Review
- Article
- Pituitary gland volumes in children with normal endocrine function.Pediatric radiology · 2023Article
- The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions.Frontiers in endocrinology · 2023Review
- Three-Dimensional Semantic Segmentation of Pituitary Adenomas Based on the Deep Learning Framework-nnU-Net: A Clinical Perspective.Micromachines · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe main aim of this study was to provide normative data for pituitary height and volume in persons between 50 and 66 years in the general population. The secondary aim was to establish a convenient surrogate marker of pituitary size for use in routine radiological practice.
methodsFrom a geographically defined prospective healthy study, 1006 participants between 50 and 66 years had a brain MRI, of which 988 (519 women) were included in this study. We measured the mid-sagittal height, max-sagittal height and total volume of the anterior pituitary lobe based on T1-weighted 3D MRI images.
resultsBoth the mean mid-sagittal and max-sagittal pituitary height were significantly larger in women compared to men, with 4.9 ± 1.7 mm versus 4.4 ± 1.4 mm (p < .001) for the mean mid-sagittal height and 6.8 ± 1.2 mm versus 6.1 ± 1.1 mm (p < 0.001) for the mean max-sagittal height. The mean anterior pituitary lobe volume was also significantly larger in women than in men (494 ± 138 mm
conclusionThis study show that women have a larger pituitary gland than men in the age group between 50 and 66 years and provides normative data for pituitary size estimates which can be used for clinical diagnostic purposes as well as future research.
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