Evidence map›Paper›PMID 33972919›Full record

ArticleNanotheranostics2021

Tracking adoptive T cell immunotherapy using magnetic particle imaging.

Angelie Rivera-Rodriguez, Lan B Hoang-Minh, Andreina Chiu-Lam, Nicole Sarna, Leyda Marrero-Morales, Duane A Mitchell, Carlos M Rinaldi-Ramos

Open access · goldAbstract read
In one paragraph

Article in Nanotheranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Magnetic nanoparticles for cancer theranostics.Biomedical physics & engineering express · 2026
    Review
  10. Advances in integrating biomaterials with CAR-T cells for enhancing solid tumor therapy.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025
    Article
  11. Article
  12. Receptor-Mediated SPION Labeling of CD4Nanomaterials (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Therapeutic mRNA vaccine applications in oncology.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. On the partial volume effect in magnetic particle imaging.Physics in medicine and biology · 2025
    Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Angelie Rivera-RodriguezJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL USA.
Lan B Hoang-MinhPreston A. Wells, Jr. Center for Brain Tumor Therapy, University of Florida, Gainesville, FL USA.
Andreina Chiu-LamDepartment of Chemical Engineering, University of Florida, Gainesville, FL USA.
Nicole SarnaJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL USA.
Leyda Marrero-MoralesJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL USA.
Duane A MitchellPreston A. Wells, Jr. Center for Brain Tumor Therapy, University of Florida, Gainesville, FL USA.
Carlos M Rinaldi-RamosJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL USA.
University of Florida · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Efficacy of Dendritic Cell Vaccines Targeting CMV in Glioblastoma (phase 2 DC vaccine)R01CA175517 · NCI · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A., SAMPSON, JOHN H. · 2015 to 2020
$3.1M
Enhancing Adoptive Immunotherapy Targeting Pediatric High-Grade GliomasR01CA195563 · NCI · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A., PACKER, ROGER · 2015 to 2019
$2.8M
NCATS NIH HHS UL1 TR001427NCI NIH HHS R01 CA175517NCI NIH HHS R01 CA195563
6 · The paper itself

Abstract

Adoptive cellular therapy (ACT) is a potent strategy to boost the immune response against cancer. ACT is effective against blood cancers but faces challenges in treating solid tumors. A critical step for the success of ACT immunotherapy is to achieve efficient trafficking and persistence of T cells to solid tumors. Non-invasive tracking of the accumulation of adoptively transferred T cells to tumors would greatly accelerate development of more effective ACT strategies. We demonstrate the use of magnetic particle imaging (MPI) to non-invasively track ACT T cells

Indexed as

Adoptive TransferBrainBrain NeoplasmsCell TrackingT-LymphocytesAnimalsMagnetite NanoparticlesMiceMice, TransgenicMagnetite Nanoparticlesbiomedical imagingbrain cancercell labelingcellular therapyiron oxide nanoparticles

Identifiers

PMID33972919
PMCPMC8100755
OpenAlexW3158053150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.