Evidence map›Paper›PMID 33972860›Full record

ArticleRoyal Society open science2021

Synthesis and pharmacological characterization of glucopyranosyl-conjugated benzyl derivatives as novel selective cytotoxic agents against colon cancer.

Boqiao Fu, Yingjie Li, Shaoyong Peng, Xiaolin Wang, Jingying Hu, Long Lv, Caifen Xia, Dai Lu, Caiqin Qin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Value of MSCT plus MRI in the Detection of Colon Cancer.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Boqiao FuHubei Provincial Collaborative Innovation Center of Biomass Resources Transformation and Utilization, College of Chemistry and Materials Science, Hubei Engineering University, Hubei 432000, People's Republic of China.ORCID 0000-0002-7022-6051
Yingjie LiGuangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, People's Republic of China.
Shaoyong PengGuangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, People's Republic of China.
Xiaolin WangGuangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, People's Republic of China.
Jingying HuState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200032, People's Republic of China.
Long LvHubei Provincial Collaborative Innovation Center of Biomass Resources Transformation and Utilization, College of Chemistry and Materials Science, Hubei Engineering University, Hubei 432000, People's Republic of China.
Caifen XiaHubei Provincial Collaborative Innovation Center of Biomass Resources Transformation and Utilization, College of Chemistry and Materials Science, Hubei Engineering University, Hubei 432000, People's Republic of China.
Dai LuDepartment of Pharmaceutical Sciences, Rangel College of Pharmacy, Texas A&M University, TX 78363, USA.
Caiqin QinHubei Provincial Collaborative Innovation Center of Biomass Resources Transformation and Utilization, College of Chemistry and Materials Science, Hubei Engineering University, Hubei 432000, People's Republic of China.
Hubei Engineering University · CNSun Yat-sen University · CNRenji Hospital · CNTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucopyranosyl-conjugated benzyl derivatives containing a [1,2,3]-triazole linker were synthesized. Benzyl served as an important pharmacophore in anti-cancer compounds. Compound

Indexed as

293Tcolon cancerglucopyanosyl-conjugated benzylHCT-116

Identifiers

PMID33972860
PMCPMC8074679
OpenAlexW3132725610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.