Evidence map›Paper›PMID 33972734›Full record

ArticleNature cell biology2021

Ankyrin G organizes membrane components to promote coupling of cell mechanics and glucose uptake.

Alicia M Salvi, Jennifer L Bays, Samantha R Mackin, René-Marc Mege, Kris A DeMali

Abstract read
In one paragraph

Article in Nature cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. E-Cadherin: A conductor of cellular signaling.Current opinion in cell biology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Tubulin Acetylation and the Cellular Mechanosensing and Stress Response.Results and problems in cell differentiation · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. A Hierarchical Mechanotransduction System: From Macro to Micro.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  12. Article
  13. Review
  14. Mechanotransduction: Forcing a change in metabolism.Current opinion in cell biology · 2023
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alicia M SalviDepartment of Biochemistry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
Jennifer L BaysDepartment of Biochemistry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
Samantha R MackinDepartment of Biochemistry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.
René-Marc MegeUniversité de Paris, CNRS, Institut Jacques Monod, Paris, France.ORCID http://orcid.org/0000-0001-8128-5543
Kris A DeMaliDepartment of Biochemistry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA. kris-demali@uiowa.edu.ORCID http://orcid.org/0000-0003-0906-1371

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Predoctoral Training in the Pharmacological SciencesT32GM067795 · NIGMS · UNIVERSITY OF IOWA · PI STRACK, STEFAN · 2004 to 2021
$3.4M
Molecular Mechanisms Underlying E-cadherin MechanotransductionR35GM136291 · NIGMS · UNIVERSITY OF IOWA · PI Kris A DeMali · 2020 to 2026
$2.8M
Investigating E-cadherin MechanotransductionF31GM135962 · NIGMS · UNIVERSITY OF IOWA · PI SALVI, ALICIA · 2020 to 2021
$50k
NCI NIH HHS P30 CA086862NIGMS NIH HHS F31 GM135962NIGMS NIH HHS R35 GM136291NIGMS NIH HHS T32 GM067795
6 · The paper itself

Abstract

The response of cells to forces is critical for their function and occurs via rearrangement of the actin cytoskeleton

Indexed as

AnkyrinsBiological TransportCarrier ProteinsCell MembraneCytoskeletonGlucoseGlucose Transporter Type 1HumansSignal TransductionAnkyrinsCarrier ProteinsGlucoseGlucose Transporter Type 1

Identifiers

PMID33972734
PMCPMC8428240

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.