Evidence map›Paper›PMID 33972720›Full record

SynthesisGenetics in medicine : official journal of the American College of Medical Genetics2021

Genetic counseling and testing for Asian Americans: a systematic review.

Jennifer L Young, Julie Mak, Talia Stanley, Michelle Bass, Mildred K Cho, Holly K Tabor

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Genetics in medicine : official journal of the American College of Medical Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jennifer L YoungStanford Center for Biomedical Ethics, Stanford University, CA, USA. youngjl@stanford.edu.
Julie MakHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, CA, USA.
Talia StanleyStanford Center for Biomedical Ethics, Stanford University, CA, USA.
Michelle BassCountway Library of Medicine, Harvard Medical School, MA, USA.
Mildred K ChoDepartment of Pediatrics, Stanford University, CA, USA.
Holly K TaborDepartment of Medicine, Stanford University, CA, USA.
Stanford University · USEthics and Public Policy Center · USUniversity of California, San Francisco · US

Funding

The Stanford Training Program in ELSI ResearchT32HG008953 · NHGRI · STANFORD UNIVERSITY · PI Mildred K. Cho, Meghan Halley · 2016 to 2026
$3.1M
NHGRI NIH HHS T32 HG008953
6 · The paper itself

Abstract

purposeAsian Americans have been understudied in the literature on genetic and genomic services. The current study systematically identified, evaluated, and summarized findings from relevant qualitative and quantitative studies on genetic health care for Asian Americans.

methodsA search of five databases (1990 to 2018) returned 8,522 unique records. After removing duplicates, abstract/title screening, and full text review, 47 studies met inclusion criteria. Data from quantitative studies were converted into "qualitized data" and pooled together with thematic data from qualitative studies to produce a set of integrated findings.

resultsSynthesis of results revealed that (1) Asian Americans are under-referred but have high uptake for genetic services, (2) linguistic/communication challenges were common and Asian Americans expected more directive genetic counseling, and (3) Asian Americans' family members were involved in testing decisions, but communication of results and risk information to family members was lower than other racial groups.

conclusionThis study identified multiple barriers to genetic counseling, testing, and care for Asian Americans, as well as gaps in the research literature. By focusing on these barriers and filling these gaps, clinical genetic approaches can be tailored to meet the needs of diverse patient groups, particularly those of Asian descent.

Indexed as

AsianGenetic CounselingFamilyHumansQualitative ResearchRacial Groups

Identifiers

PMID33972720
PMCPMC11973605
OpenAlexW3161443289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.