ArticlePediatric research2022
Early prediction of neurodevelopmental outcomes at 12 years in children born extremely preterm.
Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- General movements and neurodevelopmental outcomes at 2 years of age in infants born very preterm.Developmental medicine and child neurology · 2026Article
- Trajectories of detailed general movements and their association with one-year developmental outcomes in very preterm, moderate-to-late preterm, and term infants.European journal of pediatrics · 2026Article
- Predicting neurodevelopmental outcomes in Australian First Nations infants: The transdiagnostic utility of early screening tools.Developmental medicine and child neurology · 2026Article
- Concurrent Validity and Inter-Rater Reliability of the Motor Optimality Score-Revised in a Neonatal Surgical Population.Journal of clinical medicine · 2025Article
- Neonatal neurodevelopmental follow-up in the UK: a survey of current practice and future recommendations.BMC pediatrics · 2025Article
- Recent challenges in children's developmental milestones.Pediatric research · 2025Article
- Association between the motor optimality score-revised and clinical variables of preterm infants.BMC pediatrics · 2025Article
- Is there a risk of developmental problems in infants born to mothers with gestational diabetes mellitus and/or pre-eclampsia?PloS one · 2025Article
- Motor predictors of cortical brain development and full-IQ in children born extremely preterm with and without discrete white matter abnormalities.Brain structure & function · 2024Article
- The Motor Optimality Score-Revised Improves Early Detection of Unilateral Cerebral Palsy in Infants with Perinatal Cerebral Stroke.Children (Basel, Switzerland) · 2024Article
- The implementation of EMI-Heart, a family-tailored early motor intervention in infants with complex congenital heart disease, in practice: a feasibility RCT.Pilot and feasibility studies · 2024Article
- Early Intervention Guided by the General Movements Examination at Term Corrected Age-Short Term Outcomes.Life (Basel, Switzerland) · 2024Article
- Using the center of pressure movement analysis in evaluating spontaneous movements in infants: a comparative study with general movements assessment.Italian journal of pediatrics · 2023Article
- Reliability of the Motor Optimality Score-Revised: A study of infants at elevated likelihood for adverse neurological outcomes.Acta paediatrica (Oslo, Norway : 1992) · 2023Article
- Smartphone application links severity of retinopathy of prematurity to early motor behavior in a cohort of high-risk preterm infants.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2023Article
- Neuromotor repertoires in infants exposed to maternal COVID-19 during pregnancy: a cohort study.BMJ open · 2023Article
- Motor Optimality Scores are significantly lower in a population of high-risk infants than in infants born moderate-late preterm.Early human development · 2022Article
- General Movement Assessment in Prediction of Neurodevelopmental Disability and Cerebral Palsy.Indian pediatrics · 2022Article
- Early Motor Repertoire of Very Preterm Infants and Relationships with 2-Year Neurodevelopment.Journal of clinical medicine · 2022Article
- Identification of risk factors in pre-term infants with abnormal general movements.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtremely preterm (EPT) birth is a major risk factor for neurodevelopmental impairments. The aim was to evaluate the predictive value of Prechtl General Movement Assessment (GMA), including the Motor Optimality Score-Revised (MOS-R), at 3 months corrected age (CA) for adverse neurodevelopmental outcome at the age of 12 years.
methodsThe GMA, including the MOS-R, was applied at 3 months CA and outcomes were assessed at 12 years by Touwen's neurological examination, the Movement Assessment Battery for Children-2, and chart reviews.
resultsFifty-three infants born EPT (33 boys, mean GA 25 weeks, mean body weight 805 ± 156 g) were included. Forty-two (79%) children participated in the follow-up (mean age 12.3 ± 0.4) and 62% of these had adverse outcomes. The MOS-R differed between groups (p = 0.007). The respective predictive values of GMA, aberrant FMs, and the MOS-R cut-off of 21 for adverse outcomes were positive predictive values (PPVs) of 1.00 and 0.77, negative predictive value of 0.47 and 0.63, sensitivity of 0.31 and 0.77, and specificity of 1.00 and 0.77.
conclusionsUsing the Prechtl GMA, including the MOS-R, at 3 months CA predicted an overall adverse neurodevelopment at 12 years, with a high PPV, specificity, and sensitivity in children born EPT. IMPACT: The Prechtl GMA, including the MOS-R, can improve early identification of long-term adverse neurodevelopmental outcomes. This is the first study to investigate the predictive value of the MOS-R for neurodevelopmental outcome at mid-school age in children born EPT. Using the GMA, including the MOS-R, is suggested as one important part of the neurological assessment at 3 months CA in children born EPT. Aberrant FMs in combination with a MOS of <21 is an indicator of an increased risk of future adverse neurodevelopment in children born EPT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.