Evidence map›Paper›PMID 33972615›Full record

ArticleScientific reports2021

Cage and maternal effects on the bacterial communities of the murine gut.

Gurdeep Singh, Andrew Brass, Sheena M Cruickshank, Christopher G Knight

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

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  12. Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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  14. Hackflex library preparation enables low-cost metagenomic profiling.bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gurdeep SinghFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, A.V. Hill Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Andrew BrassFaculty of Biology, Medicine and Health, Division of Informatics, Imaging and Data Sciences, Stopford Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Sheena M CruickshankFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, A.V. Hill Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK. Sheena.Cruickshank@manchester.ac.uk.
Christopher G KnightFaculty of Science and Engineering, School of Earth and Environmental Sciences, Michael Smith Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Manchester Academic Health Science Centre · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Findings from gut microbiome studies are strongly influenced by both experimental and analytical factors that can unintentionally bias their interpretation. Environment is also critical. Both co-housing and maternal effects are expected to affect microbiomes and have the potential to confound other manipulated factors, such as genetics. We therefore analysed microbiome data from a mouse experiment using littermate controls and tested differences among genotypes (wildtype versus colitis prone-mdr1a

Indexed as

Gastrointestinal MicrobiomeAdolescentAdultAge FactorsAnimalsATP Binding Cassette Transporter, Subfamily BColitisColonDisease Models, AnimalDNA, BacterialFecesHumansIntestinal MucosaMaleMiceMice, KnockoutATP Binding Cassette Transporter, Subfamily BDNA, Bacterialmultidrug resistance protein 3RNA, Ribosomal, 16S

Identifiers

PMID33972615
PMCPMC8110963
OpenAlexW3163198128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.