Evidence map›Paper›PMID 33972607›Full record

ArticleScientific reports2021

Feasibility of large-scale population testing for SARS-CoV-2 detection by self-testing at home.

Paula Iruzubieta, Tatiana Fernández-Lanas, Laura Rasines, Lorena Cayon, Ana Álvarez-Cancelo, Alvaro Santos-Laso, Agustín García-Blanco, Soraya Curiel-Olmo, Joaquín Cabezas, Reinhard Wallmann and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Lateral Flow Immunoassays for SARS-CoV-2.Diagnostics (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Paula IruzubietaGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Tatiana Fernández-LanasGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Laura RasinesGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Lorena CayonGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Ana Álvarez-CanceloGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Alvaro Santos-LasoGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Agustín García-BlancoGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Soraya Curiel-OlmoGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Joaquín CabezasGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Reinhard WallmannDivision of Epidemiology and Computational Biology, Cantabria University School of Medicine, Santander, Spain.
Emilio FábregaGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain.
Víctor M Martínez-TaboadaDivision of Rheumatology, Marqués de Valdecilla University Hospital, IDIVAL, Santander, Spain.
José L HernándezDepartment of Internal Medicine, Marqués de Valdecilla University Hospital, IDIVAL, University of Cantabria, Santander, Spain.
Marcos López-HoyosImmunology Department, Marqués de Valdecilla University Hospital, IDIVAL, Santander, Spain.
Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.
Javier CrespoGastroenterology and Hepatology Department, Marqués de Valdecilla University Hospital, Clinical and Translational Digestive Research Group, University of Cantabria, IDIVAL, Santander, Spain. javier.crespo@scsalud.es.
Marqués de Valdecilla University Hospital · ESUniversidad de Cantabria · ESInstituto de Investigación Marqués de Valdecilla · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The simplicity and low cost of rapid point-of-care tests greatly facilitate large-scale population testing, which can contribute to controlling the spread of the COVID-19 virus. We evaluated the applicability of a self-testing strategy for SARS-CoV2 in a population-based, cross-sectional study in Cantabria, Spain, between April and May 2020. For the self-testing strategy, participants received the necessary material for the self-collection of blood and performance of a rapid antibody test using lateral flow immunoassay at home without the supervision of healthcare personnel. A total of 1,022 participants were enrolled. Most participants correctly performed the COVID-19 self-test the first time (91.3% [95% CI 89.4-92.9]). Only a minority of the participants (0.7%) needed the help of healthcare personnel, while 6.9% required a second kit delivery, for a total valid test result in 96.9% of the participants. Incorrect use of the self-test was not associated with the educational level, age over 65, or housing area. Prevalence of IgG antibodies against SARS-CoV2 for subjects with a valid rapid test result was 3.1% (95% CI 2.2-4.4), similar to the seroprevalence result obtained using a conventional approach carried out by healthcare professionals. In conclusion, COVID-19 self-testing should be considered as a screening tool.

Indexed as

Self-TestingAdolescentAdultAgedCohort StudiesCOVID-19Cross-Sectional StudiesFeasibility StudiesFemaleHumansImmunoglobulin GMaleMiddle AgedSARS-CoV-2SpainYoung AdultImmunoglobulin G

Identifiers

PMID33972607
PMCPMC8110575
OpenAlexW3163937972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.