Evidence map›Paper›PMID 33972439›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE.

Takayuki Nagae, Masashi Unno, Taiki Koizumi, Yohei Miyanoiri, Tomotsumi Fujisawa, Kento Masui, Takanari Kamo, Kei Wada, Toshihiko Eki, Yutaka Ito and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Genomic analysis highlights a novel class of DPCF-type cyanobacteriochrome.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Cyanobacteriochromes: A Rainbow of Photoreceptors.Annual review of microbiology · 2024
    Review
  6. Cyanobacteriochromes: A Rainbow of Photoreceptors.Annual review of microbiology · 2024
    Review
  7. Article
  8. Article
  9. Direct evidence for a deprotonated lysine serving as a H-bond "acceptor" in a photoreceptor protein.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Light- and pH-dependent structural changes in cyanobacteriochrome AnPixJg2.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  14. Crystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Takayuki NagaeSynchrotron Radiation Research Center, Nagoya University, Nagoya 464-8603, Japan.ORCID 0000-0001-7016-5183
Masashi UnnoDepartment of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Saga 840-8502, Japan; unno@cc.saga-u.ac.jp hirose@chem.tut.ac.jp mmisima@toyaku.ac.jp.ORCID 0000-0002-5016-6274
Taiki KoizumiDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji 192-0397, Japan.
Yohei MiyanoiriInstitute for Protein Research, Osaka University, Osaka 565-0871, Japan.ORCID 0000-0001-6889-5160
Tomotsumi FujisawaDepartment of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Saga 840-8502, Japan.ORCID 0000-0002-3282-6814
Kento MasuiDepartment of Environmental and Life Sciences, Toyohashi University of Technology, Aichi 441-8580, Japan.
Takanari KamoDepartment of Environmental and Life Sciences, Toyohashi University of Technology, Aichi 441-8580, Japan.
Kei WadaDepartment of Medical Sciences, University of Miyazaki, Miyazaki 889-1692, Japan.
Toshihiko EkiDepartment of Environmental and Life Sciences, Toyohashi University of Technology, Aichi 441-8580, Japan.ORCID 0000-0003-1553-8279
Yutaka ItoDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji 192-0397, Japan.ORCID 0000-0002-1030-4660
Yuu HiroseDepartment of Environmental and Life Sciences, Toyohashi University of Technology, Aichi 441-8580, Japan; unno@cc.saga-u.ac.jp hirose@chem.tut.ac.jp mmisima@toyaku.ac.jp.ORCID 0000-0003-1116-8979
Masaki MishimaDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji 192-0397, Japan; unno@cc.saga-u.ac.jp hirose@chem.tut.ac.jp mmisima@toyaku.ac.jp.ORCID 0000-0001-7626-7287
Toyohashi University of Technology · JPTokyo Metropolitan University · JPSaga University · JPNagoya University · JPProtein Research Foundation · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanobacteriochromes (CBCRs) are bilin-binding photosensors of the phytochrome superfamily that show remarkable spectral diversity. The green/red CBCR subfamily is important for regulating chromatic acclimation of photosynthetic antenna in cyanobacteria and is applied for optogenetic control of gene expression in synthetic biology. It is suggested that the absorption change of this subfamily is caused by the bilin C15

Indexed as

ProtonsBacterial ProteinsBile PigmentsBinding SitesCloning, MolecularCrystallography, X-RayCyanobacteriaEscherichia coliGene ExpressionGenetic VectorsHydrogen BondingHydrophobic and Hydrophilic InteractionsLightLight-Harvesting Protein ComplexesMolecular Dynamics SimulationPhotoreceptors, MicrobialBacterial ProteinsBile PigmentsLight-Harvesting Protein ComplexesPhotoreceptors, MicrobialPhytochromeProtonsPyrrolesRcaE protein, cyanobacteriaRecombinant ProteinscrystallographycyanobacteriochromeNMRphytochrome

Identifiers

PMID33972439
PMCPMC8157938
OpenAlexW3160137868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.