Evidence map›Paper›PMID 33972427›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The circadian clock ensures successful DNA replication in cyanobacteria.

Yi Liao, Michael J Rust

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Synchronization of the circadian clock to the environment tracked in real time.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yi LiaoDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637.
Michael J RustDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637; mrust@uchicago.edu.
University of Chicago · US

Funding

Coupling between Circadian Rhythms and Metaboilsm in CyanobacteriaR01GM107369 · NIGMS · UNIVERSITY OF CHICAGO · PI RUST, MICHAEL · 2013 to 2017
$1.5M
The Biochemistry of Clock Function in Fluctuating EnvironmentsR01GM135382 · NIGMS · UNIVERSITY OF CHICAGO · PI RUST, MICHAEL · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM107369NIGMS NIH HHS R01 GM135382
6 · The paper itself

Abstract

Disruption of circadian rhythms causes decreased health and fitness, and evidence from multiple organisms links clock disruption to dysregulation of the cell cycle. However, the function of circadian regulation for the essential process of DNA replication remains elusive. Here, we demonstrate that in the cyanobacterium

Indexed as

DNA ReplicationGene Expression Regulation, BacterialBacterial ProteinsCell CycleCircadian ClocksCircadian RhythmComputer SimulationModels, StatisticalPhotoperiodSynechococcusBacterial Proteinscell cyclecircadian clockcyanobacteriaDNA replicationmathematical modeling

Identifiers

PMID33972427
PMCPMC8157973
OpenAlexW3160645878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.