ArticleProceedings of the National Academy of Sciences of the United States of America2021
GABAergic synapses suppress intestinal innate immunity via insulin signaling in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- NMDA Receptor Subunit NMR-2 Regulates Pathogen-Induced Immune Responses via the Nervous System inbioRxiv : the preprint server for biology · 2026Article
- Neuronal tetraspanin TSP-6 suppresses intestinal innate immunity by modulating dense-core vesicle release in Caenorhabditis elegans.Cell communication and signaling : CCS · 2026Article
- Enteric nervous system and inflammatory bowel disease.Gastroenterology report · 2026Review
- Chelerythrine enhances anti-fungi immunity inFrontiers in immunology · 2026Article
- Modifying microbially derived short chain fatty acids to promote health.The Journal of physiology · 2026Review
- Neurotransmitter signaling in molecular and behavioral immune responses to pathogens inMicrobiology and molecular biology reviews : MMBR · 2025Review
- Patterns of pathogenesis in innate immunity: insights from C. elegans.Nature reviews. Immunology · 2025Review
- Experimental Models and Their Applicability in Inflammation Studies: Rodents, Fish, and Nematodes.International journal of molecular sciences · 2025Review
- Article
- Rpl12 is a conserved ribophagy receptor.Nature cell biology · 2025Article
- Review
- Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning.Nature communications · 2025Article
- Frontiers and future perspectives of neuroimmunology.Fundamental research · 2024Review
- Dissecting the Neuronal Contributions of the Lipid Regulator NHR-49 Function in Lifespan and Behavior inLife (Basel, Switzerland) · 2023Article
- UNC-49 is a redox-sensitive GABAScience advances · 2023Article
- Gut microbiota combined with fecal metabolomics reveals the effects of FuFang Runzaoling on the microbial and metabolic profiles in NOD mouse model of Sjögren's syndrome.BMC complementary medicine and therapies · 2023Article
- A gonadal gap junction INX-14/Notch GLP-1 signaling axis suppresses gut defense through an intestinal lysosome pathway.Frontiers in immunology · 2023Article
- Inhibition of GABAA receptors in intestinal stem cells prevents chemoradiotherapy-induced intestinal toxicity.The Journal of experimental medicine · 2022Article
- Gut neuroendocrine signaling regulates synaptic assembly in C. elegans.EMBO reports · 2022Article
- Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury.Molecular & cellular proteomics : MCP · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
GABAergic neurotransmission constitutes a major inhibitory signaling mechanism that plays crucial roles in central nervous system physiology and immune cell immunomodulation. However, its roles in innate immunity remain unclear. Here, we report that deficiency in the GABAergic neuromuscular junctions (NMJs) of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.