Evidence map›Paper›PMID 33972395›Full record

ArticleMolecular and cellular biology2021

Erf Affects Commitment and Differentiation of Osteoprogenitor Cells in Cranial Sutures via the Retinoic Acid Pathway.

Angeliki Vogiatzi, Ismini Baltsavia, Emmanuel Dialynas, Vasiliki Theodorou, Yan Zhou, Elena Deligianni, Ioannis Iliopoulos, Andrew O M Wilkie, Stephen R F Twigg, George Mavrothalassitis

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Angeliki VogiatziMedical School, University of Crete, Heraklion, Crete, Greece.
Ismini BaltsaviaMedical School, University of Crete, Heraklion, Crete, Greece.
Emmanuel DialynasIMBB, FORTH, Heraklion, Crete, Greece.
Vasiliki TheodorouIMBB, FORTH, Heraklion, Crete, Greece.
Yan ZhouMRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Elena DeligianniIMBB, FORTH, Heraklion, Crete, Greece.
Ioannis IliopoulosMedical School, University of Crete, Heraklion, Crete, Greece.
Andrew O M WilkieMRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Stephen R F TwiggMRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
George MavrothalassitisMedical School, University of Crete, Heraklion, Crete, Greece.
University of Crete · GRFORTH Institute of Molecular Biology and Biotechnology · GRUniversity of Oxford · GB

Funding

Department of HealthMedical Research Council G0902418Medical Research Council MC_UU_12025Wellcome Trust 093329Wellcome Trust 102731Wellcome Trust 102731/Z/13/Z
6 · The paper itself

Abstract

ETS2 repressor factor (ERF) haploinsufficiency causes late-onset craniosynostosis (CRS) (OMIM entry 600775; CRS4) in humans, while in mice Erf insufficiency also leads to a similar multisuture synostosis phenotype preceded by mildly reduced calvarium ossification. However, neither the cell types affected nor the effects

Indexed as

AnimalsCell DifferentiationCell ProliferationCranial SuturesCraniosynostosesMiceOsteogenesisPhenotypeStem CellsTretinoinTretinoincraniosynostosisEts transcription factorsmesenchymal stem cellsretinoic acid

Identifiers

PMID33972395
PMCPMC8300784
OpenAlexW3160543329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.