Evidence map›Paper›PMID 33972355›Full record

ArticleJournal of bacteriology2021

Reconstructing a Wild-Type Pseudomonas aeruginosa Reference Strain PAO1.

Samuel Lee, Larry Gallagher, Colin Manoil

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Inactivation of MexT inJournal of bacteriology · 2026
    Article
  3. Article
  4. Modulation of themBio · 2025
    Article
  5. Article
  6. Article
  7. Inactivation of MexT inbioRxiv : the preprint server for biology · 2025
    Article
  8. Increased susceptibility to azithromycin of Pseudomonas aeruginosa biofilms using RPMI 1640 testing media.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2024
    Article
  9. 'Wild Type'.Microbiology (Reading, England) · 2024
    Review
  10. Microbiology spectrum · 2024
    Article
  11. Article
  12. Article
  13. Microevolution of theFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samuel LeeDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Larry GallagherDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Colin ManoilDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
University of Washington · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

The P. aeruginosa reference strain PAO1 has been used to delineate much of the physiology, metabolism, and fundamental biology of the species. The wild-type parent of PAO1 was lost, and PAO1 carries a regulatory mutation introduced for positive genetic selection that affects antibiotic resistance, virulence, quorum sensing, and other traits. The mutation is a loss-of-function change in an oxidoreductase gene (

Indexed as

Bacterial ProteinsDNA Transposable ElementsGene Expression Regulation, BacterialMutagenesis, InsertionalMutationPseudomonas aeruginosaTransformation, BacterialBacterial ProteinsDNA Transposable ElementsmexSmexTShasodium antiporter

Identifiers

PMID33972355
PMCPMC8223932
OpenAlexW3160149018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.