Evidence map›Paper›PMID 33972298›Full record

ArticleBMJ case reports2021

Role of immunotherapy in oligometastatic nonsmall cell lung cancer.

Yehuda Galili, Ahmad El-Far, Jennifer Tseng, Steve Carlan

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yehuda GaliliDepartment of Medicine, Division of Hematology and Oncology, Orlando Health Corp, Orlando, Florida, USA.
Ahmad El-FarDivision of Hematology and Oncology, UF Health Cancer Center-Orlando Health, Orlando, Florida, USA.
Jennifer TsengDepartment of Medicine, Division of Hematology and Oncology, Orlando Health Corp, Orlando, Florida, USA.
Steve CarlanDepartment of Obstetrics and Gynecology, Orlando Health Corp, Orlando, Florida, USA stevecarlan@gmail.com.ORCID http://orcid.org/0000-0001-9867-8538

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The approach to metastatic lung cancer has long been focused on palliation therapy and comfort care. Recently, significant subsets of patients who suffer from a limited form of the disease have shown curative outcomes. The oligometastatic disease theory was first introduced in 1995, and since has been applied to many solid tumours. In oligometastatic nonsmall cell lung cancer, current treatment strategies include surgery, radiation therapy and chemotherapy. There is evidence of astounding survival benefits in selected patients treated with immune checkpoint inhibitors. We present three cases with oligometastatic nonsmall cell lung cancer treated with pembrolizumab, an immune checkpoint inhibitor, and describe the outcomes. Immunotherapy with pembrolizumab appears to be an effective adjunctive treatment with low toxicity in oligometastatic nonsmall cell lung cancer.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansImmunotherapyPalliative CareTreatment Outcomecancer interventionmalignant disease and immunosuppressionneuroimagingradiotherapyrespiratory cancer

Identifiers

PMID33972298
PMCPMC8112438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.