Evidence map›Paper›PMID 33972254›Full record

ArticleAntimicrobial agents and chemotherapy2021

Antifungal Susceptibility and Mutations in the Squalene Epoxidase Gene in Dermatophytes of the Trichophyton mentagrophytes Species Complex.

Xue Kong, Chao Tang, Ashutosh Singh, Sarah A Ahmed, Abdullah M S Al-Hatmi, Anuradha Chowdhary, Pietro Nenoff, Yvonne Gräser, Steven Hainsworth, Ping Zhan and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Deciphering the genomic landscape ofMicrobial genomics · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  11. Global Emergence ofInfection and drug resistance · 2026
    Review
  12. Does the use of topical azoles have an impact on antifungal resistance?The Journal of antimicrobial chemotherapy · 2025
    Article
  13. Review
  14. National Belgian Study on Terbinafine Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Antifungal Susceptibility ofAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Microbiology spectrum · 2025
    Article
  19. Review
  20. Emergence of resistant dermatophytosis caused byMedical mycology case reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 6 countries.

Xue KongDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, China.
Chao TangCenter of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Ashutosh SinghMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Sarah A AhmedCenter of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Abdullah M S Al-HatmiCenter of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Anuradha ChowdharyMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Pietro NenoffLaboratory for Medical Microbiology, Mölbis, Germany.
Yvonne GräserUniversitätsmedizin Berlin-Charité, Institut für Mikrobiologie und Hygiene, Nationales Konsiliarlabor für Dermatophyten, Berlin, Germany.
Steven HainsworthSchool of Science, RMIT University (Bundoora Campus), Bundoora, Australia.
Ping ZhanDermatology Hospital of Jiangxi Provinces, Jiangxi Dermatology Institute, Nanchang, China.
Jacques F MeisCenter of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Paul E VerweijCenter of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Weida LiuDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, China.
G Sybren de HoogDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, China.
Radboud University Nijmegen · NLUniversity of Delhi · INChinese Academy of Medical Sciences & Peking Union Medical College · CNInstitut für Hygiene und Umwelt · DEJiangxi Chest Hospital · CNRMIT University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the past decade, a prolonged and serious outbreak of dermatophytosis due to a terbinafine-resistant novel species in the Trichophyton mentagrophytes

Indexed as

ArthrodermataceaeTrichophytonAntifungal AgentsDrug Resistance, FungalMicrobial Sensitivity TestsMutationSqualene MonooxygenaseAntifungal AgentsSqualene Monooxygenaseantifungal susceptibility testingsqualene epoxidase geneTrichophyton mentagrophytes-T. interdigitale complex

Identifiers

PMID33972254
PMCPMC8284460
OpenAlexW3163749324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.