ReviewClinics in dermatology
Clinicopathologic correlations of COVID-19-related cutaneous manifestations with special emphasis on histopathologic patterns.
Review in Clinics in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Occurrence of erythema multiforme following COVID-19 vaccination: a review.Clinical and experimental vaccine research · 2023Review
- Dermatopathology of COVID-19 infection and vaccination.Pathologie (Heidelberg, Germany) · 2022Review
- Erythema Multiforme after BNT162b2 Vaccination.Internal medicine (Tokyo, Japan) · 2022Article
- Chilblain-like lesions onset during SARS-CoV-2 infection in a COVID-19-vaccinated adolescent: case report and review of literature.Italian journal of pediatrics · 2022Review
- Cutaneous manifestations of COVID-19 in a tertiary COVID-19 referral hospital in the Philippines.JAAD international · 2022Article
- Cutaneous Manifestations of SARS-CoV-2 Infection.American journal of clinical dermatology · 2022Review
- Complanatuside alleviates inflammatory cell damage induced by pro-inflammatory cytokines in skin keratinocytes.Frontiers in chemistry · 2022Article
- Erythema multiforme after third COVID-19 vaccination (Pfizer-BioNTech).Proceedings (Baylor University. Medical Center) · 2022Article
- Do we miss rare adverse events induced by COVID-19 vaccination?Frontiers in medicine · 2022Review
- Atypical erythema multiforme related to BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine.International journal of dermatology · 2021Article
- Multisystem Inflammatory Syndrome Associated with SARS-CoV-2 Infection in an Adult: A Case Report from the Maldives.Tropical medicine and infectious disease · 2021Article
- The crucial role of clinicopathological correlation in COVID-19-related cutaneous manifestations.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021Article
- SARS-CoV-2 and Skin: The Pathologist's Point of View.Biomolecules · 2021Article
- Virology and Etiopathogenesis of COVID-19 with Special Reference to Cutaneous Implications.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin is one of target organs affected by the novel coronavirus SARS-CoV-2, and in response to the current COVID-19 pandemic, a fast body of literature has emerged on related cutaneous manifestations. Current perspective is that the skin is not only a bystander of the general cytokines storm with thrombophilic multiorgan injury, but it is directly affected by the epithelial tropism of the virus, as confirmed by the detection of SARS-CoV-2 in endothelial cells and epithelial cells of epidermis and eccrine glands. In contrast with the abundance of epidemiologic and clinical reports, histopathologic characterization of skin manifestations is limited. Without an adequate clinicopathologic correlation, nosology of clinically similar conditions is confusing, and effective association with COVID-19 remains presumptive. Several patients with different types of skin lesions, including the most specific acral chilblains-like lesions, showed negative results at SARS-CoV-2 nasopharyngeal and serologic sampling. The aim of this review is to provide an overview of what has currently been reported worldwide, with a particular emphasis on microscopic patterns of the skin manifestations in patients exposed to or affected by COVID-19. Substantial breakthroughs may occur in the near future from more skin biopsies, improvement of immunohistochemistry studies, RNA detection of SARS-CoV-2 strain by real-time polymerase chain reaction-based assay, and electron microscopic studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.