Evidence map›Paper›PMID 33971928›Full record

ArticleTrials2021

Improvement of freezing of gait in patients with Parkinson's disease by music exercise therapy: a study protocol for a randomized controlled trial.

Kun-Peng Li, Zong-Lei Zhou, Ru-Zhen Zhou, Yan Zhu, Zeng-Qiao Zhang

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kun-Peng Li *Department of Neurological Rehabilitation, Shanghai Second Rehabilitation Hospital, No. 25, Lane 860, Changjiang Road, Baoshan District, Shanghai, 200441, China.
Zong-Lei Zhou *West China School of Public Health, Sichuan University, Chengdu, China.
Ru-Zhen ZhouDepartment of Neurological Rehabilitation, Shanghai Second Rehabilitation Hospital, No. 25, Lane 860, Changjiang Road, Baoshan District, Shanghai, 200441, China.
Yan ZhuDepartment of Neurological Rehabilitation, Shanghai Second Rehabilitation Hospital, No. 25, Lane 860, Changjiang Road, Baoshan District, Shanghai, 200441, China. 80743682@qq.com.
Zeng-Qiao ZhangDepartment of Neurological Rehabilitation, Shanghai Second Rehabilitation Hospital, No. 25, Lane 860, Changjiang Road, Baoshan District, Shanghai, 200441, China. 2218592583@qq.com.
Shanghai University of Traditional Chinese Medicine · CNSichuan University · CN

Funding

Shanghai characteristic diagnosis and treatment technology improvement project of traditional Chinese medicine ZY (2018-2020) -ZYJS-04Youth project of Shanghai Municipal Health Commission 20184Y0179
6 · The paper itself

Abstract

backgroundProgression of freezing of gait, a common pathological gait in Parkinson's disease, is an important risk factor for diagnosing the disease and has been shown to predispose patients to easy falls, loss of independent living ability, and reduced quality of life. Treating Parkinson's disease with freezing of gait is very difficult, while the use of medicine and operation has been ineffective. Music exercise therapy, which entails listening to music as you exercise, has been proposed as a treatment technology that can change patients' behavior, emotions, and physiological activity. In recent years, music exercise therapy has been widely used in treatment of motor disorders and neurological diseases and achieved remarkable results. Results from our earlier pilot study revealed that music exercise therapy can improve the freezing of gait of Parkinson's patients and improve their quality of life. Therefore, we aim to validate clinical efficacy of this therapy on freezing of gait of Parkinson's patients using a larger sample size. METHODS/

designThis three-arm randomized controlled trial will evaluate clinical efficacy of music exercise therapy in improving the freezing of gait in Parkinson's patients. We will recruit a total of 81 inpatients with Parkinson's disease, who meet the trial criteria. The patients will randomly receive music exercise with and without music as well as routine rehabilitation therapies, followed by analysis of changes in their gait and limb motor function after 4 weeks of intervention. We will first use a three-dimensional gait analysis system to evaluate changes in patients' gait, followed by assessment of their limb function, activity of daily living and fall risk. DISCUSSION: The findings of this trial are expected to affirm the clinical application of this therapy for future management of the disease.

trial registrationChinese Clinical Trial Registry ChiCTR1900026063 . Registered on September 20, 2019.

Indexed as

Gait Disorders, NeurologicMusicParkinson DiseaseExercise TherapyGaitHumansPilot ProjectsQuality of LifeRandomized Controlled Trials as TopicFreezing of gaitMotor functionMusic exercise therapyParkinson’s disease

Identifiers

PMID33971928
PMCPMC8112051
OpenAlexW3160474921

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.