Evidence map›Paper›PMID 33971910›Full record

ReviewJournal of nanobiotechnology2021

Recent advances in near-infrared II imaging technology for biological detection.

Nan-Nan Zhang, Chen-Ying Lu, Min-Jiang Chen, Xiao-Ling Xu, Gao-Feng Shu, Yong-Zhong Du, Jian-Song Ji

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  7. Binocular vision fusion enhanced 3D NIR-IIFundamental research · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nan-Nan Zhang *Key Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Lishui Hospital, Zhejiang University School of Medicine, Lishui, 323000, Zhejiang, China.
Chen-Ying Lu *Key Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Lishui Hospital, Zhejiang University School of Medicine, Lishui, 323000, Zhejiang, China.
Min-Jiang ChenKey Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Lishui Hospital, Zhejiang University School of Medicine, Lishui, 323000, Zhejiang, China.
Xiao-Ling XuInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Gao-Feng ShuKey Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Lishui Hospital, Zhejiang University School of Medicine, Lishui, 323000, Zhejiang, China.
Yong-Zhong DuInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. duyongzhong@zju.edu.cn.
Jian-Song JiKey Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Lishui Hospital, Zhejiang University School of Medicine, Lishui, 323000, Zhejiang, China. jijiansong@zju.edu.cn.

Funding

China Postdoctoral Science Foundation funded project 2020M681902Postdoctoral Foundation of ZheJiang province ZJ2020034the National key Research and Development projects intergovernmental cooperation in science and technology of China 2018YFE0126900the National Natural Science Foundation of China 81901852the National Natural Science Foundation of China 82072026
6 · The paper itself

Abstract

Molecular imaging technology enables us to observe the physiological or pathological processes in living tissue at the molecular level to accurately diagnose diseases at an early stage. Optical imaging can be employed to achieve the dynamic monitoring of tissue and pathological processes and has promising applications in biomedicine. The traditional first near-infrared (NIR-I) window (NIR-I, range from 700 to 900 nm) imaging technique has been available for more than two decades and has been extensively utilized in clinical diagnosis, treatment and scientific research. Compared with NIR-I, the second NIR window optical imaging (NIR-II, range from 1000 to 1700 nm) technology has low autofluorescence, a high signal-to-noise ratio, a high tissue penetration depth and a large Stokes shift. Recently, this technology has attracted significant attention and has also become a heavily researched topic in biomedicine. In this study, the optical characteristics of different fluorescence nanoprobes and the latest reports regarding the application of NIR-II nanoprobes in different biological tissues will be described. Furthermore, the existing problems and future application perspectives of NIR-II optical imaging probes will also be discussed.

Indexed as

Infrared RaysAnimalsBiomedical TechnologyDrug LiberationFluorescenceHumansMolecular ImagingNeoplasmsOptical ImagingSignal-To-Noise RatioStem CellsSurgery, Computer-AssistedBiomedical applicationsFluorescence imagingSecond near-infrared (NIR-II) window

Identifiers

PMID33971910
PMCPMC8112043

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.