Evidence map›Paper›PMID 33971824›Full record

Trial reportBMC gastroenterology2021

Impact of second forward-view examination on adenoma detection rate during unsedated colonoscopy: a randomized controlled trial.

Keshu Shan, Hongpeng Lu, Zhixin Zhang, Jiarong Xie, Lu Xu, Weihong Wang, Chunjiu Hu, Lei Xu

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03619122 (Impact of Second Forward View Examination of Proximal Colon on Adenoma Detection Rate), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03619122 nacompletednot on this map

Impact of Second Forward View Examination of Proximal Colon on Adenoma Detection Rate: A Randomized Clinical Trial

TypeinterventionalSponsorNingbo No. 1 HospitalRan2018 to 2019Enrolled392ConditionsColon AdenomaArmsSecond Examination
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Keshu ShanChina Department of Gastroenterology, Ningbo First Hospital, 59 Liuting St, Ningbo, 315010, Zhejiang, China.
Hongpeng LuChina Department of Gastroenterology, Ningbo First Hospital, 59 Liuting St, Ningbo, 315010, Zhejiang, China.
Zhixin ZhangCollege of Medicine, Ningbo University, Ningbo, 315010, Zhejiang, China.
Jiarong XieCollege of Medicine, Ningbo University, Ningbo, 315010, Zhejiang, China.
Lu XuCollege of Medicine, Ningbo University, Ningbo, 315010, Zhejiang, China.
Weihong WangChina Department of Gastroenterology, Ningbo First Hospital, 59 Liuting St, Ningbo, 315010, Zhejiang, China.
Chunjiu HuChina Department of Gastroenterology, Ningbo First Hospital, 59 Liuting St, Ningbo, 315010, Zhejiang, China.
Lei XuChina Department of Gastroenterology, Ningbo First Hospital, 59 Liuting St, Ningbo, 315010, Zhejiang, China. xulei22@163.com.
Ningbo First Hospital · CNNingbo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesColorectal cancer on the right side of the colon has been suggested to be harder to detect by colonoscopy. The aim of this study was to evaluate whether a second forward-view examination of the right side of the colon could increase the adenoma detection rate (ADR) and/or polyp detection rate (PDR).

methodsThis was a single-centre randomized controlled trial. Patients undergoing colonoscopy were recruited and randomly assigned to the second forward-view examination (SFE) group, in which the right side of the colon was examined twice or the traditional colonoscopy (TC) group in which the colonoscopy was performed in a standard manner. The primary outcome was the ADR of right colon. The overall PDR and ADR, PDR of the right colon, per-adenoma miss rate of the right colon, and advanced lesion detection rate were also recorded and compared.

resultsA total of 392 patients were included in the study (SFE group 197 vs. TC group 195). The ADR and PDR of the right colon in the SFE group were significantly higher than those in the TC group (ADR 10.7% vs. 5.1%; P = 0.042); PDR 17.8% vs. 9.7%, P = 0.021). No significant difference was found in overall PDR/ADR, or advanced lesion detection rate between the two groups.

conclusionsThis prospective controlled study revealed that a second forward-view examination could modestly increase the ADR and PDR of the right colon during unsedated colonoscopies. This simple, safe and time-effective technique might be recommended for routine unsedated colonoscopy.

trial registrationClinical Trials.gov, NCT03619122. Registered on 7/8/2018.

Indexed as

AdenomaColonic NeoplasmsColonic PolypsColorectal NeoplasmsColonoscopyHumansProspective StudiesAdenoma detection rateColonic polypsColonoscopyColorectal cancerPolyp detection rateSecond forward-view examination

Identifiers

PMID33971824
PMCPMC8111781
OpenAlexW3162799619

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.