Evidence map›Paper›PMID 33971661›Full record

ArticleCerebrovascular diseases (Basel, Switzerland)2021

Early Experience with Comaneci, a Newly FDA-Approved Controllable Assist Device for Wide-Necked Intracranial Aneurysm Coiling.

M Asif Taqi, Eytan Raz, Anastasia Vechera, Maksim Shapiro, Rishi Gupta, Joseph Haynes, Philipp Taussky, Ramesh Grandhi, Howard A Riina, Peter Kim Nelson and 1 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cerebrovascular diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M Asif TaqiVascular Neurology of Southern California, Thousand Oaks, California, USA.
Eytan RazDepartment of Radiology, Section of Neurointerventional Radiology, NYU Langone Health, New York, New York, USA.
Anastasia VecheraVascular Neurology of Southern California, Thousand Oaks, California, USA.
Maksim ShapiroDepartment of Radiology, Section of Neurointerventional Radiology, NYU Langone Health, New York, New York, USA.
Rishi GuptaDepartment of Neurosurgery, Wellstar Medical Group, Kennestone Hospital, Atlanta, Georgia, USA.
Joseph HaynesSchool of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
Philipp TausskyDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA.
Ramesh GrandhiDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA.
Howard A RiinaDepartment of Neurosurgery, NYU Langone Health, New York, New York, USA.
Peter Kim NelsonDepartment of Radiology, Section of Neurointerventional Radiology, NYU Langone Health, New York, New York, USA.
Erez NossekDepartment of Neurosurgery, NYU Langone Health, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComaneci (Rapid Medical) is a compliant, adjustable mesh that provides temporary scaffolding during coiling of wide-necked intracranial aneurysms (WNAs) that preserves antegrade flow. We report our early multi-institutional experience with the Comaneci device in the USA.

methodWe reviewed all patients with WNAs that were treated using the Comaneci device for coil remodeling of ruptured and unruptured aneurysms at 4 institutions between July 2019 and May 2020. Clinical characteristics, angiographic variables, and endovascular results were assessed.

resultsA total of 26 patients were included (18 women). The mean age was 62.7 years (range 44-81). Fifteen patients presented with ruptured aneurysms and 11 with unruptured aneurysms. The mean aneurysm neck width was 3.91 mm (range 1.9-6.5) with a mean dome-to-neck ratio of 1.57 (range 0.59-3.39). The mean maximum width was 5.80 mm (range 3.0-9.9) and the mean maximum height was 5.61 mm (range 2.0-11.8). Successful aneurysm occlusion was achieved in 25 of 26 patients. Complete occlusion was achieved in 16 patients, near-complete occlusion was observed in 9 patients, and 1 patient demonstrated residual filling. The mean time of device exposure was 24 min (range 8-76). No vasospasm was observed at the device location. Clot formation on the device was noted in 2 separate cases, but there were no clinical sequelae. There was 1 intraprocedural complication in a case that involved the simultaneous use of 2 Comaneci devices.

conclusionsOur initial experience shows that the Comaneci device is a promising and reliable tool that can safely support coil remodeling of WNAs.

Indexed as

AdultAgedAged, 80 and overDevice ApprovalEmbolization, TherapeuticEquipment DesignFemaleHumansIntracranial AneurysmMaleMiddle AgedRetrospective StudiesTreatment OutcomeUnited StatesUnited States Food and Drug AdministrationAneurysmBridging deviceCoil embolizationComaneci

Identifiers

PMID33971661
PMCPMC8315690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.