Evidence map›Paper›PMID 33971625›Full record

ArticleAging2021

Morphology-based radiomics signature: a novel determinant to identify multiple intracranial aneurysms rupture.

Xin Tong, Xin Feng, Fei Peng, Hao Niu, Baorui Zhang, Fei Yuan, Weitao Jin, Zhongxue Wu, Yuanli Zhao, Aihua Liu and 1 more

Open access · greenAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 7 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  6. Systematic Review of Radiomics and Artificial Intelligence in Intracranial Aneurysm Management.Journal of neuroimaging : official journal of the American Society of Neuroimaging
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Xin TongBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xin FengDepartment of Neurosurgery, Beijing Hospital, National Center of Gerontology, Graduate School of Peking Union Medical College, Beijing, China.
Fei PengBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Hao NiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Baorui ZhangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Fei YuanBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Weitao JinDepartment of Neurosurgery, Peking University International Hospital, Beijing, China.
Zhongxue WuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Yuanli ZhaoDepartment of Neurosurgery, Peking University International Hospital, Beijing, China.
Aihua LiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Daming WangDepartment of Neurosurgery, Beijing Hospital, National Center of Gerontology, Graduate School of Peking Union Medical College, Beijing, China.
Beijing Tian Tan Hospital · CNCapital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University International Hospital · CNBeijing Institute of Neurosurgery · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to develop and validate a morphology-based radiomics signature nomogram for assessing the risk of intracranial aneurysm (IA) rupture. A total of 254 aneurysms in 105 patients with subarachnoid hemorrhage and multiple intracranial aneurysms from three centers were retrospectively reviewed and randomly divided into the derivation and validation cohorts. Radiomics morphological features were automatically extracted from digital subtraction angiography and selected by the least absolute shrinkage and selection operator algorithm to develop a radiomics signature. A radiomics signature-based nomogram was developed by incorporating the signature and traditional morphological features. The performance of calibration, discrimination, and clinical usefulness of the nomogram was assessed. Ten radiomics morphological features were selected to build the radiomics signature model, which showed better discrimination with an area under the curve (AUC) equal to 0.814 and 0.835 in the derivation and validation cohorts compared with 0.747 and 0.666 in the traditional model, which only include traditional morphological features. When radiomics signature and traditional morphological features were combined, the AUC increased to 0.842 and 0.849 in the derivation and validation cohorts, thus showing better performance in assessing aneurysm rupture risk. This novel model could be useful for decision-making and risk stratification for patients with IAs.

Indexed as

AlgorithmsNomogramsHumansIntracranial AneurysmRetrospective StudiesRiskROC CurveTomography, X-Ray Computedintracranial aneurysmnomogramradiomics featuresradiomics signaturerisk prediction

Identifiers

PMID33971625
PMCPMC8148474
OpenAlexW3160214860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.