ArticleJournal of the American Academy of Child and Adolescent Psychiatry2021
Editorial: The Early Phenotype of Bipolar Disorder?
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In patients with bipolar disorder (BD), there is often a substantial delay before diagnosis and accurate treatment initiation. This delay is associated with a poorer outcome and stresses the importance of early recognition. As BD runs in families, longitudinal studies on children of parents with BD can provide information on the onset and early trajectories of BD. In the past 3 decades, a number of longitudinal studies on offspring of parents with BD have been initiated. With a typical age of onset in late adolescence, most of these studies started in adolescence. Thus far, these studies have shown that 13% to 25% of these children develop BD, they are predominantly at risk for developing mood disorders (>50%), and BD typically starts with a (mild) depressive episode followed by (sub)clinical mania.
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