Evidence map›Paper›PMID 33971202›Full record

ArticleJournal of neuroscience methods2021

Comparison of corticospinal tract integrity measures extracted from standard versus native space in chronic stroke.

Allison F Lewis, Jill C Stewart

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroscience methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allison F LewisDepartment of Exercise Science, University of South Carolina, Columbia, SC, 29201, USA. Electronic address: af10@email.sc.edu.
Jill C StewartDepartment of Exercise Science, University of South Carolina, Columbia, SC, 29201, USA. Electronic address: jcstewar@mailbox.sc.edu.
University of South Carolina · US

Funding

Targeted Engagement of the Premotor-Prefrontal Motor Circuit after StrokeR03HD087481 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI STEWART, JILL CAMPBELL · 2016 to 2017
$141k
American Heart Association-American Stroke Association 15SDG24970011NICHD NIH HHS R03 HD087481
6 · The paper itself

Abstract

backgroundFractional anisotropy (FA) and mean diffusivity (MD) are measures derived from diffusion-weighted imaging that represent the integrity of the corticospinal tract (CST) after stroke. Some studies of the motor system after stroke extract FA and MD from native space while others extract from standard space making comparison across studies challenging. NEW

methodThe purpose was to compare CST integrity measures extracted from standard versus native space in individuals with chronic stroke. Twenty-four individuals with stroke underwent diffusion-weighted imaging and motor impairment assessment. The spatial location of the CST was identified using four commonly utilized approaches; therefore, our results are applicable to a variety of approaches.

resultsFA extracted from standard space (FA COMPARISON WITH EXISTING METHOD(S): Our study shows that extraction space influences diffusion-based microstructural integrity values (FA and MD) of the CST in individuals with stroke, which is important when considering methods for aggregating CST integrity data across studies. The relationship between CST integrity and motor impairment appears to be robust to extraction space.

conclusionsThe differences we identified are important for comparing FA and MD values across studies that use different extraction space. Our results provide context for future meta-analyses of diffusion-based metrics of CST integrity in individuals with stroke.

Indexed as

Pyramidal TractsStrokeAnisotropyDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansDiffusion-weighted imagingFractional anisotropyMean diffusivityStroke

Identifiers

PMID33971202
PMCPMC8205992
OpenAlexW3160643240

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.