Evidence map›Paper›PMID 33971111›Full record

ArticleAmerican journal of respiratory cell and molecular biology2021

SARS-CoV-2 Infection Is Associated with Reduced Krüppel-like Factor 2 in Human Lung Autopsy.

David Wu, Tzu-Han Lee, Ru-Ting Huang, Robert D Guzy, Nathan Schoettler, Ayodeji Adegunsoye, Jeffrey Mueller, Aliya Husain, Anne I Sperling, Gökhan M Mutlu and 1 more

Open access · hybridAbstract readLetter
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

David WuThe University of Chicago Chicago, Illinois.ORCID 0000-0003-3162-3238
Tzu-Han LeeThe University of Chicago Chicago, Illinois.
Ru-Ting HuangThe University of Chicago Chicago, Illinois.ORCID 0000-0001-8360-9994
Robert D GuzyThe University of Chicago Chicago, Illinois.ORCID 0000-0001-8420-6177
Nathan SchoettlerThe University of Chicago Chicago, Illinois.
Ayodeji AdegunsoyeThe University of Chicago Chicago, Illinois.
Jeffrey MuellerThe University of Chicago Chicago, Illinois.
Aliya HusainThe University of Chicago Chicago, Illinois.
Anne I SperlingThe University of Chicago Chicago, Illinois.
Gökhan M MutluThe University of Chicago Chicago, Illinois.ORCID 0000-0002-2056-612X
Yun FangThe University of Chicago Chicago, Illinois.ORCID 0000-0003-4597-3095
University of Chicago · US

Funding

Role of alveolar macrophages in particulate matter-induced cardiopulmonary diseaseR01ES015024 · NIEHS · UNIVERSITY OF CHICAGO · PI MUTLU, GOKHAN M. · 2006 to 2022
$6.1M
Coronary artery disease locus 1p32.2 and miR92a-PPAP2B signaling in endothelial mechanobiologyR01HL136765 · NHLBI · UNIVERSITY OF CHICAGO · PI FANG, YUN · 2017 to 2021
$2.0M
Spatial Delivery of MicroRNA Inhibitor via Targeted Polyelectrolyte Complex Micelles to Treat Atherosclerosis.R01HL138223 · NHLBI · UNIVERSITY OF CHICAGO · PI FANG, YUN · 2017 to 2021
$2.0M
Improving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810k
Genetics of Asthma Sub-Phenotypes Impact Gene Regulation in Cell-Specific PatternsK08HL153955 · NHLBI · UNIVERSITY OF CHICAGO · PI SCHOETTLER, NATHAN R · 2020 to 2024
$785k
Regulation of vascular metabolism in acute lung injuryR00HL145113 · NHLBI · UNIVERSITY OF CHICAGO · PI WU, DAVID D · 2021 to 2022
$341k
Regulation of vascular metabolism in acute lung injuryK99HL145113 · NHLBI · UNIVERSITY OF CHICAGO · PI WU, DAVID D · 2019 to 2020
$320k
NHLBI NIH HHS K08 HL153955NHLBI NIH HHS K23 HL146942NHLBI NIH HHS K99 HL145113NHLBI NIH HHS L30 HL154452NHLBI NIH HHS R00 HL145113NHLBI NIH HHS R01 HL136765NHLBI NIH HHS R01 HL138223NIEHS NIH HHS R01 ES015024
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutopsyCOVID-19FemaleHumansKruppel-Like Transcription FactorsLungMaleRespiratory MucosaSARS-CoV-2KLF2 protein, humanKruppel-Like Transcription Factors

Identifiers

PMID33971111
PMCPMC8399572
OpenAlexW3160414668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.