ArticlePLoS computational biology2021
CRIMSON: An open-source software framework for cardiovascular integrated modelling and simulation.
Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed.
- Review
- Article
- Hemodynamic impact of acute liver injury on cardiac function: An in silico study via a closed-loop cardiovascular model.PLoS computational biology · 2026Article
- Comparative Analysis of Open-Source Finite Element Method Solvers for Computational Fluid Dynamics Performance in a Carotid Artery Model.Journal of biomechanical engineering · 2026Article
- An open-source computational framework for immersed fluid-structure interaction modeling using FEBio and MFEM.Engineering with computers · 2026Article
- Computational Analysis of Disease Progression in Pediatric Pulmonary Arterial Hypertension.ArXiv · 2025Article
- A systematic evaluation of the impact of contralateral stenosis on ipsilateral internal carotid artery hemodynamics using computational fluid dynamics.Quantitative imaging in medicine and surgery · 2025Article
- Dynamic Fractional Flow Reserve from 4D-CTA: A Novel Framework for Non-Invasive Coronary Assessment.Journal of imaging · 2025Article
- Predicting Cerebral Aneurysm Rupture: The Role of Computational Fluid Dynamics.Neuroimaging clinics of North America · 2025Review
- Tube2FEM: a general-purpose highly automated pipeline for flow-related processes in (embedded) tubular objects.Royal Society open science · 2025Article
- The Robust Vessel Segmentation and Centerline Extraction: One-Stage Deep Learning Approach.Journal of imaging · 2025Article
- Deployment of a digital twin using the coupled momentum method for fluid-structure interaction: A case study for aortic aneurysm.Computers in biology and medicine · 2025Article
- Pediatric Cardiovascular Multiscale Modeling using a Functional Mock-up Interface.Cardiovascular engineering and technology · 2025Article
- DIRECT MEDICAL IMAGE TO SIMULATION USING AUTO-SEGMENTATION AND POINT CLOUD-BASED CFD.Advances in computational science and engineering · 2025Article
- Nitric Oxide Distribution Correlates with Intraluminal Thrombus in Abdominal Aortic Aneurysm: A Computational Study.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Hemodynamic characteristics and clinical treatment of patients with iliac vein compression syndrome.Frontiers in surgery · 2025Review
- SeqSeg: Learning Local Segments for Automatic Vascular Model Construction.Annals of biomedical engineering · 2025Article
- svZeroDSolver: A modular package for lumped-parameter cardiovascular simulations.Journal of open source software · 2025Article
Corrections and comments
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Authors and funding
34 authors.
Funding
Abstract
In this work, we describe the CRIMSON (CardiovasculaR Integrated Modelling and SimulatiON) software environment. CRIMSON provides a powerful, customizable and user-friendly system for performing three-dimensional and reduced-order computational haemodynamics studies via a pipeline which involves: 1) segmenting vascular structures from medical images; 2) constructing analytic arterial and venous geometric models; 3) performing finite element mesh generation; 4) designing, and 5) applying boundary conditions; 6) running incompressible Navier-Stokes simulations of blood flow with fluid-structure interaction capabilities; and 7) post-processing and visualizing the results, including velocity, pressure and wall shear stress fields. A key aim of CRIMSON is to create a software environment that makes powerful computational haemodynamics tools accessible to a wide audience, including clinicians and students, both within our research laboratories and throughout the community. The overall philosophy is to leverage best-in-class open source standards for medical image processing, parallel flow computation, geometric solid modelling, data assimilation, and mesh generation. It is actively used by researchers in Europe, North and South America, Asia, and Australia. It has been applied to numerous clinical problems; we illustrate applications of CRIMSON to real-world problems using examples ranging from pre-operative surgical planning to medical device design optimization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.