HDAC Inhibition in the Heart: Erasing Hidden Fibrosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters.The journal of cardiovascular aging · 2026
   Article
2. A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling.Nature communications · 2025
   Article
3. Emerging Insights into Sall4's Role in Cardiac Regenerative Medicine.Cells · 2025
   Review
4. The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis.Nature communications · 2025
   Article
5. Epigenetic Regulation in Myocardial Fibroblasts and Its Impact on Cardiovascular Diseases.Pharmaceuticals (Basel, Switzerland) · 2024
   Review
6. Fibroblast Diversity and Epigenetic Regulation in Cardiac Fibrosis.International journal of molecular sciences · 2024
   Review
7. The recent advance and prospect of natural source compounds for the treatment of heart failure.Heliyon · 2024
   Review
8. Unlocking Macrophage Secrets: Histone Deacetylases in Chronic Transplant Rejection.Results and problems in cell differentiation · 2024
   Review
9. Traditional Therapeutics and Potential Epidrugs for CVD: Why Not Both?Life (Basel, Switzerland) · 2023
   Review
10. Inflammatory Mechanisms in Heart Failure with Preserved Ejection Fraction.Physiology (Bethesda, Md.) · 2023
    Review
11. The role of P21-activated kinase (Pak1) in sinus node function.Journal of molecular and cellular cardiology · 2023
    Article
12. Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotype.American journal of physiology. Heart and circulatory physiology · 2023
    Article
13. The Current Therapeutic Role of Chromatin Remodeling for the Prognosis and Treatment of Heart Failure.Biomedicines · 2023
    Review
14. Prediction of histone deacetylase inhibition by triazole compounds based on artificial intelligence.Frontiers in pharmacology · 2023
    Article
15. Exploring epigenetic reprogramming during central nervous system infection.Immunological reviews · 2022
    Review
16. Targeting the cytoskeleton and extracellular matrix in cardiovascular disease drug discovery.Expert opinion on drug discovery · 2022
    Review
17. Epigenetic Regulation of Heart Failure: Cell Type Matters.Circulation research · 2021
    Article
18. Cumulative evidence for associations between variants in the histone deacetylases genes and cardio-cerebrovascular diseases: A systematic review and meta-analysis.JRSM cardiovascular disease
    Article

Corrections and comments

• Comment on
  HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.2021

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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