ArticleNeuropsychology2021
Periventricular and deep abnormal white matter differ in associations with cognitive performance at midlife.
Open access · hybridAbstract read
In one paragraph
Article in Neuropsychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume.Stroke · 2026Article
- Cognitive reserve against vascular contributions to cognitive impairment and dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Association of Fractional Anisotropy in White Matter Bundles with Plasma Biomarkers of Neurodegeneration and Glial Reactivity in Individuals with Cognitive Complaints without dementia.Research square · 2026Article
- Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume.medRxiv : the preprint server for health sciences · 2025Article
- The genetic and environmental etiology of novel frequency-driven regional parcellations of abnormal white matter.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025Article
- No sex differences in the association between regional brain structure abnormalities and cognitive functioning in a geriatric memory clinic population.Aging brain · 2025Article
- Association of the Brain White Matter Hyperintensity with the Cognitive Performance in Middle-Aged Population.Cerebrovascular diseases (Basel, Switzerland) · 2025Article
- Elevated Plasma Protein Carbonyl Concentration Is Associated with More Abnormal White Matter in People with HIV.Viruses · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 1 country.
Mark Sanderson-CiminoJoint Doctoral Program in Clinical Psychology, San Diego State/University of California.ORCID 0000-0002-5872-3186
Matthew S PanizzonCenter for Behavior Genetics of Aging, University of California.
Jeremy A ElmanCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-5840-1769
Xin TuFamily Medicine and Public Health, University of California.
Daniel E GustavsonCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-1470-4928
Olivia PuckettCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-5073-2563
Karalani CrossDepartment of Psychiatry University of California.
Randy NotestineDepartment of Psychiatry University of California.
Sean N HattonCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-9149-8726
Lisa T EylerDepartment of Psychiatry University of California.ORCID 0000-0002-7783-8798
Linda K McEvoyDepartment of Radiology, University of California, San Diego.
Donald J HaglerDepartment of Radiology, University of California, San Diego.
Michael C NealeVirginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University.ORCID 0000-0003-4887-659X
Nathan A GillespieVirginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University.
Michael J LyonsDepartment of Psychological and Brain Sciences, Boston University.
Carol E FranzCenter for Behavior Genetics of Aging, University of California.
Christine Fennema-NotestineCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-6527-6361
William S KremenCenter for Behavior Genetics of Aging, University of California.ORCID 0000-0002-8629-5609
University of California, San Francisco · USUniversity of California San Diego · USVirginia Commonwealth University · USBoston University · USCalifornia Department of Public Health · USSan Diego State University · US
Funding
The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4)R01AG050595 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELMAN, JEREMY A, FRANZ, CAROL ELAINE · 2015 to 2024
$28.0MThe VETSA Longitudinal MRI Twin Study of AgingR01AG022381 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KREMEN, WILLIAM S. · 2003 to 2019
$22.3MUrban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2018 to 2022
$11.5MEffects of Androgen Deprivation Therapy on Preclinical Symptoms of Alzheimer's DiseaseR01AG056410 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PANIZZON, MATTHEW S · 2017 to 2021
$3.3MSES health gradients in late life: testing models of gene-environment interplay in an international twin consortiumR01AG059329 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, BRIAN K., GATZ, MARGARET · 2018 to 2022
$2.9MModerate alcohol use: risk or protective factor for age-related cognitive decline, mild cognitive impairment, and brain health in agingR01AG062483 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCEVOY, LINDA KATHLEEN · 2019 to 2021
$1.6MPractice Effects in Cognitive Aging: Implications for Biomarkers and Early DiagnosisF31AG064834 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDERSON-CIMINO, MARK · 2020 to 2021
$78kDesert-Pacific Mental Illness Research Education and Clinical CenterNational Institute of Health; National Institute on AgingNIA NIH HHS F31 AG064834NIA NIH HHS P01 AG055367NIA NIH HHS R01 AG022381NIA NIH HHS R01 AG050595NIA NIH HHS R01 AG056410NIA NIH HHS R01 AG059329NIA NIH HHS R01 AG062483
Abstract
PubMed holds no abstract for this paper.
Indexed as
Executive FunctionMemory, EpisodicMemory, Short-TermAgedCognitionCognitive DysfunctionHumansIndependent LivingLeukoencephalopathiesMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsOrgan SizeRisk FactorsWhite Matter
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.