Evidence map›Paper›PMID 33970532›Full record

ArticleMicrobiologyOpen2021

Magnesium depletion extends fission yeast lifespan via general amino acid control activation.

Hokuto Ohtsuka, Mikuto Kobayashi, Takafumi Shimasaki, Teppei Sato, Genki Akanuma, Yasuyuki Kitaura, Yoko Otsubo, Akira Yamashita, Hirofumi Aiba

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Extension of chronological lifespan in Schizosaccharomyces pombe.Genes to cells : devoted to molecular & cellular mechanisms · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hokuto OhtsukaLaboratory of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.ORCID 0000-0001-7843-2602
Mikuto KobayashiLaboratory of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Takafumi ShimasakiLaboratory of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Teppei SatoLaboratory of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.
Genki AkanumaDepartment of Life Science, College of Sciences, Rikkyo University, Tokyo, Japan.
Yasuyuki KitauraLaboratory of Nutritional Biochemistry, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.
Yoko OtsuboLaboratory of Cell Responses, National Institute for Basic Biology, Okazaki, Japan.
Akira YamashitaLaboratory of Cell Responses, National Institute for Basic Biology, Okazaki, Japan.
Hirofumi AibaLaboratory of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.ORCID 0000-0002-7775-0446
Nagoya University · JPNational Institute for Basic Biology · JPRikkyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrients including glucose, nitrogen, sulfur, zinc, and iron are involved in the regulation of chronological lifespan (CLS) of yeast, which serves as a model of the lifespan of differentiated cells of higher organisms. Herein, we show that magnesium (Mg

Indexed as

Amino AcidsCell CycleGene Expression Regulation, FungalGenes, FungalLongevityMagnesiumNuclear ProteinsNutrientsRibosomesSchizosaccharomycesSchizosaccharomyces pombe ProteinsAmino AcidsEcl1 protein, S pombeMagnesiumNuclear ProteinsNutrientsSchizosaccharomyces pombe Proteinschronological lifespanEcl1 family genefission yeastGAACmagnesium

Identifiers

PMID33970532
PMCPMC8088111
OpenAlexW3161667410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.