Evidence map›Paper›PMID 33970466›Full record

Observational studyNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2021

α

Ari Dienel, Remya A Veettil, Kanako Matsumura, Jude P J Savarraj, H Alex Choi, Peeyush Kumar T, Jaroslaw Aronowski, Pramod Dash, Spiros L Blackburn, Devin W McBride

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Agonism of the αExperimental neurology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ari DienelThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Remya A VeettilThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Kanako MatsumuraThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Jude P J SavarrajThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
H Alex ChoiThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Peeyush Kumar TThe University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA.
Jaroslaw AronowskiThe University of Texas McGovern Medical School, Houston, TX, USA.
Pramod DashDepartment of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Spiros L BlackburnThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA.
Devin W McBrideThe Vivian L Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center At Houston, Houston, TX, USA. devin.w.mcbride@uth.tmc.edu.ORCID http://orcid.org/0000-0001-8988-3353
The University of Texas Health Science Center at Houston · USThe University of Texas Health Science Center · US

Funding

Role of Haptoglobin Genotype on Neuroinflammation and Coagulation Following Aneurysmal Subarachnoid HemorrhageK23NS106054 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BLACKBURN, SPIROS · 2018 to 2022
$875k
NINDS NIH HHS K23 NS106054
6 · The paper itself

Abstract

Aneurysmal subarachnoid hemorrhage (aSAH) causes a robust inflammatory response which leads worse brain injury and poor outcomes. We investigated if stimulation of nicotinic acetylcholine α

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorAnimalsBiomarkersCholinesterase InhibitorsFemaleGalantamineHumansInflammation MediatorsMaleMiceNeuroinflammatory DiseasesSignal TransductionSubarachnoid Hemorrhagealpha7 Nicotinic Acetylcholine ReceptorBiomarkersCholinesterase InhibitorsGalantamineInflammation MediatorsGalantamineNeuroinflammationNicotinic acetylcholine receptorSubarachnoid hemorrhage

Identifiers

PMID33970466
PMCPMC8609090
OpenAlexW3163611890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.