ArticleJapanese journal of radiology2021
Application of multimodal ultrasonography for differentiating benign and malignant cervical lymphadenopathy.
Article in Japanese journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Elastography for distinguishing lymphoma from benign and metastatic lymphadenopathy: a systematic review and Bayesian meta-analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Pooled it
- Diagnostic Accuracy of Multiparametric Ultrasound Versus Cross-Sectional Imaging for Differentiating Benign and Malignant Cervical Lymph Nodes: A Histopathology-Referenced Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- Differentiation of Benign and Malignant Cervical Lymph Nodes Using a Multi-Modal Ultrasound-Based Machine Learning Model With SHAP Interpretability.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Review
- Dual-mode 3D shear wave elastography with qualitative and quantitative assessment improves diagnosis of inguinal lymph node metastasis.Quantitative imaging in medicine and surgery · 2026Article
- Contrast-enhanced ultrasound (CEUS) in diagnosis of Kikuchi disease: how to distinguish it from lymphoma?Quantitative imaging in medicine and surgery · 2025Article
- High-frequency contrast-enhanced ultrasound in discriminating benign and malignant superficial lymph nodes: a diagnostic comparison.BMC cancer · 2025Article
- Ultrasonography and sonoelastography in cervical lymph node differentiation: A cross-sectional study.Bioinformation · 2025Article
- Ultrasound-based Node-RADS: Introducing a new Scoring System for Ultrasound-based Classification of Lymphadenopathy.Iranian journal of otorhinolaryngology · 2025Article
- Multimodality high-frequency ultrasound in the evaluation of cervical malignant lymphoma before biopsy.Future oncology (London, England) · 2024Article
- Value of conventional ultrasound and shear‑wave elastography in the assessment of mesenteric lymphadenitis in a paediatric population.Experimental and therapeutic medicine · 2024Article
- Diagnosis of cervical lymphoma using a YOLO-v7-based model with transfer learning.Scientific reports · 2024Article
- Current State of Artificial Intelligence in Clinical Applications for Head and Neck MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023Review
- Cine MR feature tracking analysis for diagnosing thymic epithelial tumors: a feasibility study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Review
- Case Report: Primary Mediastinal Large B-Cell Lymphoma Invasion of Extranodal Thyroid Tissue Mimicking Tuberculosis and Confounded by Similar Ultrasonic Appearance.Frontiers in oncology · 2022Article
- Differential Diagnosis Value of Shear-Wave Elastography for Superficial Enlarged Lymph Nodes.Frontiers in oncology · 2022Article
- Indication of perfusion contrast-enhanced ultrasound for diagnosing lymph nodes.Japanese journal of radiology · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of this study was to evaluate the diagnostic value of multimodal ultrasonography, including SWE and CEUS, for the differentiation of benign and malignant cervical lymphadenopathy.
methodsA total of 103 patients with 109 enlarged neck lymph nodes underwent SWE and CEUS. There were 25 hyperplastic lymph nodes, 66 metastatic lymph nodes, and 18 cases of lymphoma.
resultsUsing 31.6 kPa as the Emax cutoff, the sensitivity, specificity and accuracy of measurements on both benign and malignant cervical lymph nodes were 55.95%, 96%, and 65.2%, respectively. CEUS showed that lymph nodes with reactive hyperplasia mainly exhibited uniform perfusion via the lymphatic hilum (18/25; 72%; P < 0.01). The main manifestation of lymphoma was uniform perfusion through the lymphatic hila (10/18; 55.6%; P < 0.01). Metastatic lymph nodes mainly exhibited uneven perfusion (57/66; 86.4%; P < 0.01). The sensitivity, specificity, and accuracy of multimodal ultrasonography for the diagnosis of benign and malignant cervical lymphadenopathies were 90.5%, 72%, and 86.2%, respectively.
conclusionsOur findings suggest that multimodal ultrasonography can detect the stiffness (elasticity), perfusion pattern, and characteristics of lymph nodes and is a valuable tool for differentiating between benign and malignant lymphadenopathies.
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