Evidence map›Paper›PMID 33970434›Full record

ArticleJournal of endocrinological investigation2021

Testing telediagnostic thyroid ultrasound in Peru: a new horizon in expanding access to imaging in rural and underserved areas.

T J Marini, S L Weiss, A Gupta, Y T Zhao, T M Baran, B Garra, I Shafiq, D C Oppenheimer, M S Egoavil, R L Ortega and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

T J MariniUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0002-1529-5097
S L WeissUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
A GuptaUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
Y T ZhaoUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.ORCID https://orcid.org/0000-0001-9010-760X
T M BaranUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
B GarraMedical Imaging Ministries of the Americas, 10810 Lake Minneola Shores, Clermont, FL, 34711, USA.
I ShafiqUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
D C OppenheimerUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
M S EgoavilMedical Innovation and Technology, Calle Los Libertadores 635, 15046, San Isidro, Peru.ORCID https://orcid.org/0000-0002-9065-2576
R L OrtegaUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
R A QuinnUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
J KanUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
A M DozierUniversity of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY, 14642, USA.
L TamayoMedical Innovation and Technology, Calle Los Libertadores 635, 15046, San Isidro, Peru.
C CarlottoMedical Innovation and Technology, Calle Los Libertadores 635, 15046, San Isidro, Peru.
B CastanedaPontifica Universidad Catolica del Peru, Av. Universitaria 1801, 15088, San Miguel, Peru. castaneda.b@pucp.edu.pe.
University of Rochester Medical Center · USGlobal Ministries · USPontificia Universidad Católica del Perú · PE

Funding

Innóvate Perú 409-FIDECOM INNOVATEPERU-PVE-2017Pontificia Universidad Católica del Perú Períodos de Investigación 2020
6 · The paper itself

Abstract

purposeThyroid ultrasound is a key tool in the evaluation of the thyroid, but billions of people around the world lack access to ultrasound imaging. In this study, we tested an asynchronous telediagnostic ultrasound system operated by individuals without prior ultrasound training which may be used to effectively evaluate the thyroid and improve access to imaging worldwide.

methodsThe telediagnostic system in this study utilizes volume sweep imaging (VSI), an imaging technique in which the operator scans the target region with simple sweeps of the ultrasound probe based on external body landmarks. Sweeps are recorded and saved as video clips for later interpretation by an expert. Two operators without prior ultrasound experience underwent 8 h of training on the thyroid VSI protocol and the operation of the telemedicine platform. After training, the operators scanned patients at a health center in Lima. Telediagnostic examinations were sent to the United States for remote interpretation. Standard of care thyroid ultrasound was performed by an experienced radiologist at the time of VSI examination to serve as a reference standard.

resultsNovice operators scanned 121 subjects with the thyroid VSI protocol. Of these exams, 88% were rated of excellent image quality showing complete or near complete thyroid visualization. There was 98.3% agreement on thyroid nodule presence between VSI teleultrasound and standard of care ultrasound (Cohen's kappa 0.91, P < 0.0001). VSI measured the thyroid size, on average, within 5 mm compared to standard of care. Readers of VSI were also able to effectively characterize thyroid nodules, and there was no significant difference in measurement of thyroid nodule size (P = 0.74) between VSI and standard of care.

conclusionThyroid VSI telediagnostic ultrasound demonstrated both excellent visualization of the thyroid gland and agreement with standard of care thyroid ultrasound for nodules and thyroid size evaluation. This system could be deployed for evaluation of palpable thyroid abnormalities, nodule follow-up, and epidemiological studies to promote global health and improve the availability of diagnostic imaging in underserved communities.

Indexed as

Health Services AccessibilityTelemedicineThyroid NoduleUltrasonographyAdultFemaleGlobal HealthHumansMaleMedically Underserved AreaPeruQuality ImprovementRural PopulationStandard of CareThyroid GlandGlobal healthGoiterTelemedicineThyroid cancerThyroid ultrasoundUltrasound

Identifiers

PMID33970434
PMCPMC8572222
OpenAlexW3161390879

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.